HitPredict

Interactor 1: SMAD1 (P70340)
Mothers against decapentaplegic homolog 1 (MAD homolog 1) (Mothers against DPP homolog 1) (Dwarfin-A) (Dwf-A) (Mothers-against-DPP-related 1) (Mad-related protein 1) (mMad1) (SMAD family member 1) (SMAD 1) (Smad1)
Gene: SMAD1

Interactor 2: Q8BTS0 (Q8BTS0)
Probable ATP-dependent RNA helicase DDX5 (EC 3.6.4.13) (DEAD box protein 5)
Gene: Ddx5

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	15464984
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0030509 - BMP signaling pathway GO:0070878 - primary miRNA binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 465 Mm			1 615
+	Hs
		571470 SMAD1_HUMAN (1-465): 0: 653: 99.14		DDX5_HUMAN (1-615): 0: 609: 98.86
+	Hs
		571568 SMAD5_HUMAN (2-465): 0: 618: 89.25		DDX5_HUMAN (1-615): 0: 609: 98.86
+	Mm
		1207259 SMAD3_MOUSE (3-465): 0: 554: 59.44		Q8BTS0_MOUSE (1-615): 0: 614: 100.00
+	Hs
		571401 SMAD3_HUMAN (3-465): 0: 554: 59.44		DDX5_HUMAN (1-615): 0: 609: 98.86
+	Mm
		1143947 SMAD2_MOUSE (3-465): 0: 539: 55.14		Q8BTS0_MOUSE (1-615): 0: 614: 100.00
+	Mm
		956548 SMAD4_MOUSE (8-454): 6.82e-151: 442: 33.33		Q8BTS0_MOUSE (1-615): 0: 614: 100.00
+	Hs
		133977 SMAD3_HUMAN (3-465): 0: 554: 59.44		DDX3X_HUMAN (3-478): 1.97e-148: 445: 38.66
+	Hs
		181693 SMAD3_HUMAN (3-465): 0: 554: 59.44		DDX3Y_HUMAN (3-485): 3.4e-148: 445: 37.40
+	Hs
		181701 SMAD2_HUMAN (3-465): 0: 537: 55.14		DDX3Y_HUMAN (3-485): 3.4e-148: 445: 37.40
+	Mm
		192488 SMAD7_MOUSE (30-131): 1.02e-24: 107: 33.33		Q8BTS0_MOUSE (1-615): 0: 614: 100.00