Interactor 1: FADI (P76503)
3-ketoacyl-CoA thiolase FadI (EC 2.3.1.16) (ACSs) (Acetyl-CoA acyltransferase) (Acyl-CoA ligase) (Beta-ketothiolase) (Fatty acid oxidation complex subunit beta)
Gene: FADI

Interactor 2: FADJ (P77399)
Fatty acid oxidation complex subunit alpha [Includes: Enoyl-CoA hydratase/3-hydroxybutyryl-CoA epimerase (EC 4.2.1.17) (EC 5.1.2.3); 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35)]
Gene: FADJ

Species: Escherichia coli K-12

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.52 1.00 0.724

The method score is based on:

Property Details
Experiments 15690043
Identification Methods tandem affinity purification, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ECH_1~Thiolase_C, 3HCDH_N~Thiolase_N, ECH_1~Thiolase_N
Common GO terms GO:0003857 - 3-hydroxyacyl-CoA dehydrogenase activity
GO:0004300 - enoyl-CoA hydratase activity
GO:0005737 - cytoplasm
GO:0006635 - fatty acid beta-oxidation
GO:0036125 - fatty acid beta-oxidation multienzyme complex
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 436
Ec

1 714
+ Hs
+ Dm
+ Hs
+ At

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Last updated: 15 Jul 2024