Protein: SYRC
Arginine--tRNA ligase, cytoplasmic (EC 6.1.1.19) (Arginyl-tRNA synthetase) (ArgRS)

Gene: SYRC, RARS1
Organism: Homo sapiens
Interactions: 199
UniProt ID: P54136

Gene Ontology (top 5):
GO:0000049 - tRNA binding
GO:0004814 - arginine-tRNA ligase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

867690

AIMP1
Aminoacyl tRNA synthase complex-interacting multifunctional protein 1

6

3

Small-scale

0.732

High

867692

AIMP2
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

6

1

Small-scale

0.731

High

814406

SYQ
Glutamine--tRNA ligase

5

4

Small-scale

0.721

High

867780

SYLC
Leucine--tRNA ligase, cytoplasmic

4

2

Small-scale

0.705

High

430900

SYEP
Bifunctional glutamate/proline--tRNA ligase

3

5

Small-scale

0.674

High

541333

SYDC
Aspartate--tRNA ligase, cytoplasmic

3

2

High-throughput

0.667

High

713384

CD68
Macrosialin

3

1

High-throughput

0.667

High

782990

SYIC
Isoleucine--tRNA ligase, cytoplasmic

3

2

Small-scale

0.667

High

867729

CMTD1
Catechol O-methyltransferase domain-containing protein 1

3

1

High-throughput

0.667

High

226960

PRKN
E3 ubiquitin-protein ligase parkin

3

1

High-throughput

0.640

High

132794

SDCB1
Syntenin-1

3

0

High-throughput

0.638

High

867758

CC115
Coiled-coil domain-containing protein 115

3

0

High-throughput

0.636

High

58224

SYTC2
Threonine--tRNA ligase 2, cytoplasmic

2

2

High-throughput

0.628

High

201579

MCA3
Eukaryotic translation elongation factor 1 epsilon-1

2

2

High-throughput

0.628

High

506942

LAMP1
Lysosome-associated membrane glycoprotein 1

2

1

High-throughput

0.628

High

867678

SYMC
Methionine--tRNA ligase, cytoplasmic

2

4

High-throughput

0.628

High

867707

SYK
Lysine--tRNA ligase

2

2

High-throughput

0.628

High

346320

MYC
Myc proto-oncogene protein

3

0

High-throughput

0.628

High

867696

CUL3
Cullin-3

2

2

High-throughput

0.611

High

560178

NCPR
NADPH--cytochrome P450 reductase

2

0

High-throughput

0.602

High

867742

NECT2
Nectin-2

2

0

High-throughput

0.602

High

528826

CFTR
Cystic fibrosis transmembrane conductance regulator

2

0

High-throughput

0.585

High

867682

WDR5
WD repeat-containing protein 5

2

1

Small-scale

0.584

High

867782

ZRAN1
Ubiquitin thioesterase ZRANB1

2

1

High-throughput

0.584

High

867756

ZN521
Zinc finger protein 521

2

0

High-throughput

0.580

High

369244

ESR1
Estrogen receptor

2

1

High-throughput

0.571

High

507923

FGFR1
Fibroblast growth factor receptor 1

2

5

High-throughput

0.571

High

867713

LARP7
La-related protein 7

2

0

High-throughput

0.559

High

373933

RAF1
RAF proto-oncogene serine/threonine-protein kinase

2

0

High-throughput

0.547

High

411652

LCK
Tyrosine-protein kinase Lck

2

0

High-throughput

0.547

High

548885

NDKA
Nucleoside diphosphate kinase A

2

0

High-throughput

0.547

High

581572

VCAM1
Vascular cell adhesion protein 1

2

0

High-throughput

0.547

High

742159

SYUA
Alpha-synuclein

2

0

High-throughput

0.547

High

128503

DNM1L
Dynamin-1-like protein

1

1

High-throughput

0.536

High

202850

EMC8
ER membrane protein complex subunit 8

1

1

High-throughput

0.536

High

440433

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

1

High-throughput

0.536

High

867693

G3BP1
Ras GTPase-activating protein-binding protein 1

1

1

High-throughput

0.536

High

867695

CUL1
Cullin-1

1

2

High-throughput

0.536

High

867785

G3BP2
Ras GTPase-activating protein-binding protein 2

1

1

High-throughput

0.536

High

867791

EMC9
ER membrane protein complex subunit 9

1

1

High-throughput

0.536

High

133396

NOP56
Nucleolar protein 56

1

0

High-throughput

0.513

High

255082

ATG13
Autophagy-related protein 13

1

0

High-throughput

0.513

High

452693

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

0

High-throughput

0.513

High

725745

SOAT1
Sterol O-acyltransferase 1

1

0

High-throughput

0.513

High

813267

CAPZB
F-actin-capping protein subunit beta

1

0

High-throughput

0.513

High

867683

RS16
Small ribosomal subunit protein uS9

1

0

High-throughput

0.513

High

867701

CAPR1
Caprin-1

1

0

High-throughput

0.513

High

867704

CND2
Condensin complex subunit 2

1

0

High-throughput

0.513

High

867710

PKN2
Serine/threonine-protein kinase N2

1

0

High-throughput

0.513

High

867717

C102B
Coiled-coil domain-containing protein 102B

1

0

High-throughput

0.513

High

867734

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.513

High

867736

PDZD8
PDZ domain-containing protein 8

1

0

High-throughput

0.513

High

867738

RIN3
Ras and Rab interactor 3

1

0

High-throughput

0.513

High

867740

PSPC1
Paraspeckle component 1

1

0

High-throughput

0.513

High

867744

TFG
Protein TFG

1

0

High-throughput

0.513

High

174745

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

2

High-throughput

0.501

High

867679

CDC42
Cell division control protein 42 homolog

1

3

High-throughput

0.501

High

867697

TF2H3
General transcription factor IIH subunit 3

1

0

High-throughput

0.493

High

867708

RNPS1
RNA-binding protein with serine-rich domain 1

1

0

High-throughput

0.493

High

269212

WBP4
WW domain-binding protein 4

1

1

High-throughput

0.481

High

867681

SUMO2
Small ubiquitin-related modifier 2

1

0

High-throughput

0.480

High

568194

TAL1
T-cell acute lymphocytic leukemia protein 1

1

0

High-throughput

0.479

High

121576

IKBE
NF-kappa-B inhibitor epsilon

1

1

High-throughput

0.479

High

130810

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

1

High-throughput

0.479

High

232825

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

1

High-throughput

0.479

High

294575

RECQ4
ATP-dependent DNA helicase Q4

1

1

High-throughput

0.479

High

326533

SNAI1
Zinc finger protein SNAI1

1

1

High-throughput

0.479

High

384553

NTRK1
High affinity nerve growth factor receptor

1

2

High-throughput

0.479

High

397864

ISG15
Ubiquitin-like protein ISG15

1

2

High-throughput

0.479

High

475518

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

2

High-throughput

0.479

High

552324

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

569455

CEBPB
CCAAT/enhancer-binding protein beta

1

1

High-throughput

0.479

High

572606

VGFR1
Vascular endothelial growth factor receptor 1

1

2

High-throughput

0.479

High

650767

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

674370

UFO
Tyrosine-protein kinase receptor UFO

1

1

High-throughput

0.479

High

684554

STIP1
Stress-induced-phosphoprotein 1

1

2

High-throughput

0.479

High

716906

CTNB1
Catenin beta-1

1

1

High-throughput

0.479

High

738181

FLT3
Receptor-type tyrosine-protein kinase FLT3

1

2

High-throughput

0.479

High

749277

BRCA1
Breast cancer type 1 susceptibility protein

1

1

High-throughput

0.479

High

779084

CCNF
Cyclin-F

1

1

High-throughput

0.479

High

808423

YAP1
Transcriptional coactivator YAP1

1

2

High-throughput

0.479

High

835602

GSK3B
Glycogen synthase kinase-3 beta

1

1

High-throughput

0.479

High

867676

UBP14
Ubiquitin carboxyl-terminal hydrolase 14

1

1

High-throughput

0.479

High

867680

UBC12
NEDD8-conjugating enzyme Ubc12

1

1

High-throughput

0.479

High

867684

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.479

High

867685

GRB2
Growth factor receptor-bound protein 2

1

1

High-throughput

0.479

High

867687

NFKB2
Nuclear factor NF-kappa-B p100 subunit

1

1

High-throughput

0.479

High

867702

GRB7
Growth factor receptor-bound protein 7

1

2

Small-scale

0.479

High

867703

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

1

Small-scale

0.479

High

867705

TNIP1
TNFAIP3-interacting protein 1

1

1

High-throughput

0.479

High

867712

ANR55
Ankyrin repeat domain-containing protein 55

1

1

High-throughput

0.479

High

867716

A16L1
Autophagy-related protein 16-1

1

2

High-throughput

0.479

High

867724

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.479

High

867732

RPTOR
Regulatory-associated protein of mTOR

1

2

High-throughput

0.479

High

867743

ESR2
Estrogen receptor beta

1

1

High-throughput

0.479

High

867745

HDAC2
Histone deacetylase 2

1

1

High-throughput

0.479

High

867747

FBXW7
F-box/WD repeat-containing protein 7

1

1

High-throughput

0.479

High

867749

ARMC5
Armadillo repeat-containing protein 5

1

1

High-throughput

0.479

High

867751

CHM4C
Charged multivesicular body protein 4c

1

1

High-throughput

0.479

High

867752

OPTN
Optineurin

1

2

High-throughput

0.479

High

867755

DDRGK
DDRGK domain-containing protein 1

1

1

High-throughput

0.479

High

867760

RING2
E3 ubiquitin-protein ligase RING2

1

2

High-throughput

0.479

High

867761

M3K14
Mitogen-activated protein kinase kinase kinase 14

1

1

High-throughput

0.479

High

867769

CCDC8
Coiled-coil domain-containing protein 8

1

1

High-throughput

0.479

High

867770

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.479

High

867781

HDAC6
Histone deacetylase 6

1

2

High-throughput

0.479

High

867787

HDAC5
Histone deacetylase 5

1

2

High-throughput

0.479

High

867793

NEMO
NF-kappa-B essential modulator

1

1

High-throughput

0.479

High

119278

LEG9
Galectin-9

1

0

High-throughput

0.458

High

125275

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

0

High-throughput

0.458

High

133942

DDX3X
ATP-dependent RNA helicase DDX3X

1

0

Small-scale

0.458

High

148574

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.458

High

182633

R113A
E3 ubiquitin-protein ligase RNF113A

1

0

High-throughput

0.458

High

298315

UFL1
E3 UFM1-protein ligase 1

1

0

High-throughput

0.458

High

303043

HEXI1
Protein HEXIM1

1

0

High-throughput

0.458

High

316487

MET18
Histidine protein methyltransferase 1 homolog

1

0

High-throughput

0.458

High

322373

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.458

High

328782

TOP3B
DNA topoisomerase 3-beta-1

1

0

High-throughput

0.458

High

338178

EGFR
Epidermal growth factor receptor

1

0

High-throughput

0.458

High

354378

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

0

High-throughput

0.458

High

429857

CATL1
Procathepsin L

1

0

High-throughput

0.458

High

521826

CADH1
Cadherin-1

1

0

High-throughput

0.458

High

584352

TNR1A
Tumor necrosis factor receptor superfamily member 1A

1

0

High-throughput

0.458

High

718653

PHB1
Prohibitin 1

1

0

High-throughput

0.458

High

719425

MERL
Merlin

1

0

High-throughput

0.458

High

720057

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

785787

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

0

High-throughput

0.458

High

807653

MAP1B
Microtubule-associated protein 1B

1

0

High-throughput

0.458

High

817828

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.458

High

823752

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.458

High

832259

MCM2
DNA replication licensing factor MCM2

1

0

High-throughput

0.458

High

867675

ATX3
Ataxin-3

1

0

High-throughput

0.458

High

867677

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.458

High

867686

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.458

High

867688

MDM2
E3 ubiquitin-protein ligase Mdm2

1

0

Small-scale

0.458

High

867689

RUNX1
Runt-related transcription factor 1

1

0

High-throughput

0.458

High

867691

NFX1
Transcriptional repressor NF-X1

1

0

High-throughput

0.458

High

867694

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

867698

PEBB
Core-binding factor subunit beta

1

0

High-throughput

0.458

High

867699

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

0

High-throughput

0.458

High

867706

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

867709

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.458

High

867711

CRY1
Cryptochrome-1

1

0

High-throughput

0.458

High

867715

RN123
E3 ubiquitin-protein ligase RNF123

1

0

High-throughput

0.458

High

867718

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

867720

CDC73
Parafibromin

1

0

High-throughput

0.458

High

867721

PRP8
Pre-mRNA-processing-splicing factor 8

1

0

High-throughput

0.458

High

867722

RICTR
Rapamycin-insensitive companion of mTOR

1

0

High-throughput

0.458

High

867725

MOB3C
MOB kinase activator 3C

1

0

High-throughput

0.458

High

867726

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.458

High

867727

ZN598
E3 ubiquitin-protein ligase ZNF598

1

0

High-throughput

0.458

High

867730

IFT20
Intraflagellar transport protein 20 homolog

1

0

High-throughput

0.458

High

867731

SLX4
Structure-specific endonuclease subunit SLX4

1

0

High-throughput

0.458

High

867733

RHG24
Rho GTPase-activating protein 24

1

0

High-throughput

0.458

High

867735

CA131
Uncharacterized protein C1orf131

1

0

High-throughput

0.458

High

867739

TIP
T-cell immunomodulatory protein

1

0

High-throughput

0.458

High

867741

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

0

High-throughput

0.458

High

867746

TANK
TRAF family member-associated NF-kappa-B activator

1

0

High-throughput

0.458

High

867748

LENG1
Leukocyte receptor cluster member 1

1

0

High-throughput

0.458

High

867750

DCPS
m7GpppX diphosphatase

1

0

High-throughput

0.458

High

867759

RUFY1
RUN and FYVE domain-containing protein 1

1

0

High-throughput

0.458

High

867762

ANM1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.458

High

867763

RIOK1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

867764

GCP2
Gamma-tubulin complex component 2

1

0

High-throughput

0.458

High

867765

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

0

High-throughput

0.458

High

867767

ACE2
Angiotensin-converting enzyme 2

1

0

High-throughput

0.458

High

867768

SPRTN
DNA-dependent metalloprotease SPRTN

1

0

High-throughput

0.458

High

867772

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

0

High-throughput

0.458

High

867773

ANLN
Anillin

1

0

High-throughput

0.458

High

867774

FBX6
F-box only protein 6

1

0

High-throughput

0.458

High

867775

RAD18
E3 ubiquitin-protein ligase RAD18

1

0

High-throughput

0.458

High

867776

PIHD1
PIH1 domain-containing protein 1

1

0

High-throughput

0.458

High

867778

WWOX
WW domain-containing oxidoreductase

1

0

High-throughput

0.458

High

867779

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

0

High-throughput

0.458

High

867783

MKRN1
E3 ubiquitin-protein ligase makorin-1

1

0

High-throughput

0.458

High

867784

BAG5
BAG family molecular chaperone regulator 5

1

0

High-throughput

0.458

High

867786

TRI33
E3 ubiquitin-protein ligase TRIM33

1

0

High-throughput

0.458

High

867788

MTMR7
Myotubularin-related protein 7

1

0

High-throughput

0.458

High

867792

LOXL2
Lysyl oxidase homolog 2

1

0

High-throughput

0.458

High

401693

JUN
Transcription factor Jun

1

1

High-throughput

0.445

High

867719

PKHA7
Pleckstrin homology domain-containing family A member 7

1

4

High-throughput

0.445

High

867737

MSPD2
Motile sperm domain-containing protein 2

1

1

High-throughput

0.445

High

867757

CEP63
Centrosomal protein of 63 kDa

1

1

High-throughput

0.445

High

990

SIM26
Small integral membrane protein 26

1

0

High-throughput

0.426

High

496633

TAU
Microtubule-associated protein tau

1

0

High-throughput

0.426

High

532446

TCTP
Translationally-controlled tumor protein

1

0

Small-scale

0.426

High

867714

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

867789

ITM2B
Integral membrane protein 2B

1

0

High-throughput

0.426

High

831139

CEBPA
CCAAT/enhancer-binding protein alpha

1

1

High-throughput

0.408

High

867771

C1QR1
Complement component C1q receptor

2

0

High-throughput

0.328

High

867754

RMC1
Regulator of MON1-CCZ1 complex

1

0

High-throughput

0.279

Low

867766

TX101
Testis-expressed protein 101

1

0

High-throughput

0.279

Low

329535

AGR2
Anterior gradient protein 2 homolog

1

0

High-throughput

0.249

Low

867700

GRM2
Metabotropic glutamate receptor 2

1

0

High-throughput

0.249

Low

867723

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

867728

ZCH18
Zinc finger CCCH domain-containing protein 18

1

0

High-throughput

0.249

Low

867753

KCD12
BTB/POZ domain-containing protein KCTD12

1

0

Small-scale

0.249

Low

867777

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

0

High-throughput

0.249

Low

867790

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024