HitPredict

Interactor 1: F1LST4 (F1LST4)
Microtubule-associated protein
Gene: Mapt

Interactor 2: HSP74 (O88600)
Heat shock 70 kDa protein 4 (Ischemia responsive 94 kDa protein)
Gene: Hspa4

Species: Rattus norvegicus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	32357304
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 775 Rn			1 840
+	Rn
		291980 TAU_RAT (1-751): 2.82e-89: 299: 99.87		HSP74_RAT (1-840): 0: 985: 100.00
+	Mm
		498021 TAU_MOUSE (1-751): 2.06e-76: 263: 89.51		Q3U2G2_MOUSE (1-840): 0: 972: 97.74
+	Mm
		497946 TAU_MOUSE (1-751): 2.06e-76: 263: 89.51		HS74L_MOUSE (1-840): 0: 962: 61.79
+	Hs
		496426 TAU_HUMAN (1-751): 1.72e-63: 228: 70.87		HSP74_HUMAN (1-840): 0: 982: 95.83
+	Mm
		498049 TAU_MOUSE (1-751): 2.06e-76: 263: 89.51		HS105_MOUSE (1-840): 0: 930: 60.93
+	Hs
		320800 TAU_HUMAN (1-751): 1.72e-63: 228: 70.87		HS74L_HUMAN (1-840): 0: 958: 62.38
+	Hs
		497367 TAU_HUMAN (1-751): 1.72e-63: 228: 70.87		HS105_HUMAN (1-840): 0: 929: 61.86
+	Hs
		554275 MUC1_HUMAN (4-330): 3.1e-11: 69.1: 11.01		HSP74_HUMAN (1-840): 0: 982: 95.83
+	Dm
		1370298 Q9VLS7_DROME (5-774): 2.51e-11: 69.7: 10.23		Q9VUC1_DROME (1-840): 0: 833: 41.38
+	Mm
		498048 TAU_MOUSE (1-751): 2.06e-76: 263: 89.51		HS71A_MOUSE (2-572): 2.47e-83: 281: 32.41
+	Mm
		497918 TAU_MOUSE (1-751): 2.06e-76: 263: 89.51		HS71L_MOUSE (564-692): 5.55e-20: 97: 22.31
+	Mm
		497989 TAU_MOUSE (1-751): 2.06e-76: 263: 89.51		HSP7C_MOUSE (564-692): 6.31e-19: 93.5: 17.69
+	Hs
		483743 TAU_HUMAN (1-751): 1.72e-63: 228: 70.87		HS71A_HUMAN (564-686): 1.27e-19: 95.9: 22.58
+	Hs
		496165 TAU_HUMAN (1-751): 1.72e-63: 228: 70.87		HSP7C_HUMAN (564-692): 2.3e-19: 95.1: 18.46
+	Hs
		496425 TAU_HUMAN (1-751): 1.72e-63: 228: 70.87		HS71L_HUMAN (564-691): 2.01e-19: 95.1: 24.03
+	Hs
		496242 TAU_HUMAN (1-751): 1.72e-63: 228: 70.87		HSP76_HUMAN (563-690): 1.91e-16: 85.8: 20.16
+	Hs
		503487 MAP4_HUMAN (20-726): 2.2e-36: 150: 21.73		HSP7C_HUMAN (564-692): 2.3e-19: 95.1: 18.46
+	Hs
		504886 NYNRI_HUMAN (254-562): 3.19e-14: 79.2: 17.13		HSP7C_HUMAN (564-692): 2.3e-19: 95.1: 18.46
+	Hs
		503745 SC24C_HUMAN (219-517): 5.76e-11: 68.4: 20.67		HSP7C_HUMAN (564-692): 2.3e-19: 95.1: 18.46
+	Hs
		483759 ANK2_HUMAN (326-568): 2.92e-10: 66.5: 18.61		HS71A_HUMAN (564-686): 1.27e-19: 95.9: 22.58