HitPredict

Interactor 1: D6R9G5 (D6R9G5)
Kelch like family member 2
Gene: KLHL2

Interactor 2: KEAP1 (Q14145)
Kelch-like ECH-associated protein 1 (Cytosolic inhibitor of Nrf2) (INrf2) (Kelch-like protein 19)
Gene: KEAP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.80	0.514

Property	Details
Experiments	28514442
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	BACK~BTB, BTB~BTB
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 144 Hs			1 624
+	Hs
		329061 KLHL2_HUMAN (1-144): 2.95e-43: 151: 70.83		KEAP1_HUMAN (1-624): 0: 582: 100.00
+	Hs
		1121551 KLHL3_HUMAN (10-144): 3.3e-28: 110: 44.44		KEAP1_HUMAN (1-624): 0: 582: 100.00
+	Hs
		329043 KLHL2_HUMAN (1-144): 2.95e-43: 151: 70.83		KLHL2_HUMAN (31-612): 1.74e-160: 474: 36.06
+	Hs
		329072 KLHL2_HUMAN (1-144): 2.95e-43: 151: 70.83		KLH26_HUMAN (43-612): 2.19e-143: 431: 26.58
+	Hs
		1200023 KLHL3_HUMAN (10-144): 3.3e-28: 110: 44.44		KLH26_HUMAN (43-612): 2.19e-143: 431: 26.58
+	Hs
		1199490 KLH26_HUMAN (58-144): 3.77e-27: 107: 31.82		KLH22_HUMAN (38-612): 1.34e-141: 427: 25.04
+	Hs
		329115 KLHL2_HUMAN (1-144): 2.95e-43: 151: 70.83		KLH13_HUMAN (424-619): 5.72e-46: 174: 30.05
+	Hs
		94339 D6R9G5_HUMAN (1-144): 6.69e-56: 173: 100.00		KLHL3_HUMAN (466-621): 5.19e-36: 144: 35.26
+	Hs
		329117 KLHL2_HUMAN (1-144): 2.95e-43: 151: 70.83		KLHL3_HUMAN (466-621): 5.19e-36: 144: 35.26
+	Hs
		94318 D6R9G5_HUMAN (1-144): 6.69e-56: 173: 100.00		KLH17_HUMAN (498-621): 6.19e-21: 99.1: 31.20
+	Hs
		94314 D6R9G5_HUMAN (1-144): 6.69e-56: 173: 100.00		KLH12_HUMAN (498-621): 1.18e-19: 94.9: 27.34
+	Hs
		1459688 KLHL3_HUMAN (10-144): 3.3e-28: 110: 44.44		KLHL3_HUMAN (466-621): 5.19e-36: 144: 35.26
+	Hs
		329077 KLHL2_HUMAN (1-144): 2.95e-43: 151: 70.83		KLH17_HUMAN (498-621): 6.19e-21: 99.1: 31.20
+	Hs
		329071 KLHL2_HUMAN (1-144): 2.95e-43: 151: 70.83		KLH12_HUMAN (498-621): 1.18e-19: 94.9: 27.34
+	Hs
		1247782 KLHL3_HUMAN (10-144): 3.3e-28: 110: 44.44		KLH17_HUMAN (498-621): 6.19e-21: 99.1: 31.20
+	Hs
		1199050 KLHL3_HUMAN (10-144): 3.3e-28: 110: 44.44		KLH12_HUMAN (498-621): 1.18e-19: 94.9: 27.34
+	Hs
		1198979 KLH26_HUMAN (58-144): 3.77e-27: 107: 31.82		KLH12_HUMAN (498-621): 1.18e-19: 94.9: 27.34
+	Hs
		161299 KLH26_HUMAN (58-144): 3.77e-27: 107: 31.82		ENC1_HUMAN (516-620): 6.55e-15: 79.9: 17.93