HitPredict

Interactor 1: RAE1L (P78406)
mRNA export factor RAE1 (Rae1 protein homolog) (mRNA-associated protein mrnp 41)
Gene: RAE1

Interactor 2: WDR59 (Q6PJI9)
GATOR2 complex protein WDR59 (WD repeat-containing protein 59)
Gene: WDR59

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	19615732
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	WD40~WD40
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 368 Hs			1 974
+	Hs
		1162302 TBL1R_HUMAN (2-160): 3.97e-41: 152: 17.71		WDR59_HUMAN (1-974): 0: 805: 100.00
+	Hs
		245613 TBL1X_HUMAN (2-160): 2.62e-39: 148: 17.14		WDR59_HUMAN (1-974): 0: 805: 100.00
+	Hs
		903313 WDR5_HUMAN (247-367): 7.8e-24: 102: 14.75		WDR59_HUMAN (1-974): 0: 805: 100.00
+	Hs
		943879 RAE1L_HUMAN (1-368): 5.99e-98: 296: 100.00		FBXW7_HUMAN (219-506): 1.23e-21: 102: 12.93
+	Hs
		943888 RAE1L_HUMAN (1-368): 5.99e-98: 296: 100.00		WDR24_HUMAN (3-165): 3.25e-20: 98.7: 12.79
+	Ce
		954053 RAE1_CAEEL (2-368): 4.91e-82: 256: 49.87		LIN53_CAEEL (104-371): 8.15e-17: 86.1: 19.07
+	Sc
		630844 NLE1_YEAST (117-366): 6.81e-45: 163: 9.40		NLE1_YEAST (144-503): 1.94e-46: 176: 13.41
+	Hs
		245633 TBL1X_HUMAN (2-160): 2.62e-39: 148: 17.14		TBL1R_HUMAN (138-486): 7.41e-43: 166: 12.16
+	Hs
		903551 NLE1_HUMAN (252-366): 5.64e-25: 107: 15.39		WDR5_HUMAN (180-476): 8.37e-46: 169: 14.38
+	Hs
		903077 WDR5_HUMAN (247-367): 7.8e-24: 102: 14.75		WDR5_HUMAN (180-476): 8.37e-46: 169: 14.38
+	Hs
		903349 WDR5_HUMAN (247-367): 7.8e-24: 102: 14.75		WDR5B_HUMAN (180-476): 5.68e-43: 161: 13.40
+	Hs
		1240442 POC1B_HUMAN (2-159): 3.19e-39: 147: 21.30		POC1A_HUMAN (268-629): 1.17e-19: 94.5: 9.52
+	Hs
		196984 WDR5_HUMAN (247-367): 7.8e-24: 102: 14.75		PRP4_HUMAN (2-175): 7.43e-33: 136: 12.85
+	Hs
		903418 WDR5_HUMAN (247-367): 7.8e-24: 102: 14.75		FBXW7_HUMAN (219-506): 1.23e-21: 102: 12.93
+	Hs
		903471 WDR5_HUMAN (247-367): 7.8e-24: 102: 14.75		GRWD1_HUMAN (96-354): 6.12e-21: 99.1: 16.60
+	Hs
		1346954 NLE1_HUMAN (252-366): 5.64e-25: 107: 15.39		NLE1_HUMAN (3-88): 1.27e-17: 89.1: 7.78
+	Hs
		903171 WDR5_HUMAN (247-367): 7.8e-24: 102: 14.75		RBBP4_HUMAN (145-377): 1.33e-17: 88.4: 20.39
+	Hs
		903428 WDR5_HUMAN (247-367): 7.8e-24: 102: 14.75		SNR40_HUMAN (268-503): 1.87e-17: 87.2: 9.09
+	Hs
		792949 WDR5_HUMAN (247-367): 7.8e-24: 102: 14.75		LIS1_HUMAN (278-527): 1.09e-16: 85.6: 8.00