Protein: SPB8
Serpin B8 (Cytoplasmic antiproteinase 2) (CAP-2) (CAP2) (Peptidase inhibitor 8) (PI-8)

Gene: SPB8, SERPINB8
Organism: Homo sapiens
Interactions: 77
UniProt ID: P50452

Gene Ontology (top 5):
GO:0004867 - serine-type endopeptidase inhibitor activity
GO:0005615 - extracellular space
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0010951 - negative regulation of endopeptidase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

767083

SPB6
Serpin B6

2

10

High-throughput

0.811

High

895430

CF298
Cilia- and flagella-associated protein 298

3

3

High-throughput

0.667

High

366283

FA10
Coagulation factor X

1

20

Small-scale

0.647

High

457955

TRY1
Serine protease 1

1

20

Small-scale

0.647

High

895463

CDK15
Cyclin-dependent kinase 15

2

7

High-throughput

0.628

High

895457

FNDC5
Fibronectin type III domain-containing protein 5

1

6

High-throughput

0.618

High

895450

TRI67
Tripartite motif-containing protein 67

1

13

High-throughput

0.618

High

302110

CDKL5
Cyclin-dependent kinase-like 5

3

3

High-throughput

0.604

High

895444

EEIG1
Early estrogen-induced gene 1 protein

2

0

High-throughput

0.602

High

895465

TMPSD
Transmembrane protease serine 13

1

20

High-throughput

0.575

High

318463

TOX4
TOX high mobility group box family member 4

2

10

High-throughput

0.574

High

895439

NONO
Non-POU domain-containing octamer-binding protein

2

2

High-throughput

0.574

High

895470

TB22B
TBC1 domain family member 22B

2

7

High-throughput

0.574

High

895471

GPT2L
G patch domain-containing protein 2-like

2

1

High-throughput

0.574

High

895475

FCF1
rRNA-processing protein FCF1 homolog

2

3

High-throughput

0.574

High

895433

KPCE
Protein kinase C epsilon type

2

4

High-throughput

0.571

High

222361

TSN6
Tetraspanin-6

1

3

High-throughput

0.536

High

292587

RENR
Renin receptor

1

5

High-throughput

0.536

High

420249

IFNA4
Interferon alpha-4

1

1

High-throughput

0.536

High

602764

AATC
Aspartate aminotransferase, cytoplasmic

1

8

High-throughput

0.536

High

733311

CCR1
C-C chemokine receptor type 1

1

7

High-throughput

0.536

High

895428

STX17
Syntaxin-17

1

9

High-throughput

0.536

High

895431

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

1

4

High-throughput

0.536

High

895432

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

9

High-throughput

0.536

High

895438

MAP7
Ensconsin

1

3

High-throughput

0.536

High

895441

ZIC1
Zinc finger protein ZIC 1

1

7

High-throughput

0.536

High

895455

SPICE
Spindle and centriole-associated protein 1

1

1

High-throughput

0.536

High

895460

TRI43
Tripartite motif-containing protein 43

1

6

High-throughput

0.536

High

895474

SSUH2
Protein SSUH2 homolog

1

8

High-throughput

0.536

High

895427

ATN1
Atrophin-1

1

1

High-throughput

0.515

High

343142

CXL14
C-X-C motif chemokine 14

1

0

High-throughput

0.513

High

640658

ZP3
Zona pellucida sperm-binding protein 3

1

0

High-throughput

0.513

High

895426

RPAB3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

1

0

High-throughput

0.513

High

895436

REG3A
Regenerating islet-derived protein 3-alpha

1

0

High-throughput

0.513

High

895442

CR1L
Complement component receptor 1-like protein

1

0

High-throughput

0.513

High

895449

RINL
Ras and Rab interactor-like protein

1

0

High-throughput

0.513

High

488748

FURIN
Furin

1

3

Small-scale

0.501

High

231216

NDUS5
NADH dehydrogenase [ubiquinone] iron-sulfur protein 5

1

1

High-throughput

0.489

High

252514

SEP15
Selenoprotein F

1

3

High-throughput

0.489

High

325307

OR2A4
Olfactory receptor 2A4

1

13

High-throughput

0.489

High

351266

OR2H2
Olfactory receptor 2H2

1

4

High-throughput

0.489

High

771833

UD13
UDP-glucuronosyltransferase 1A3

1

3

High-throughput

0.489

High

895425

ASCL1
Achaete-scute homolog 1

1

4

High-throughput

0.489

High

895429

DSCR6
Protein ripply3

1

7

High-throughput

0.489

High

895434

HEN2
Helix-loop-helix protein 2

1

2

High-throughput

0.489

High

895435

EMX2
Homeobox protein EMX2

1

1

High-throughput

0.489

High

895443

ANR39
Ankyrin repeat domain-containing protein 39

1

7

High-throughput

0.489

High

895446

AMTN
Amelotin

1

1

High-throughput

0.489

High

895451

MOGT3
2-acylglycerol O-acyltransferase 3

1

6

High-throughput

0.489

High

895452

ZC3C1
Zinc finger C3HC-type protein 1

1

4

High-throughput

0.489

High

895453

COA5
Cytochrome c oxidase assembly factor 5

1

2

High-throughput

0.489

High

895456

ZN713
Zinc finger protein 713

1

2

High-throughput

0.489

High

895458

O13C3
Olfactory receptor 13C3

1

4

High-throughput

0.489

High

895461

SARAF
Store-operated calcium entry-associated regulatory factor

1

7

High-throughput

0.489

High

895464

MMTA2
Multiple myeloma tumor-associated protein 2

1

5

High-throughput

0.489

High

895467

PRD12
PR domain zinc finger protein 12

1

5

High-throughput

0.489

High

895468

HES4
Transcription factor HES-4

1

4

High-throughput

0.489

High

895469

TSSP
Thymus-specific serine protease

1

4

High-throughput

0.489

High

522063

BCL2
Apoptosis regulator Bcl-2

1

2

Small-scale

0.479

High

872082

SOX2
Transcription factor SOX-2

1

10

High-throughput

0.479

High

887844

MCM2
DNA replication licensing factor MCM2

1

6

High-throughput

0.479

High

895466

WDR33
pre-mRNA 3' end processing protein WDR33

1

8

High-throughput

0.470

High

895472

TA2R8
Taste receptor type 2 member 8

1

1

High-throughput

0.470

High

895445

A16L1
Autophagy-related protein 16-1

1

10

High-throughput

0.445

High

261131

NSMA
Sphingomyelin phosphodiesterase 2

1

7

High-throughput

0.407

High

895448

TIFAB
TRAF-interacting protein with FHA domain-containing protein B

1

2

High-throughput

0.407

High

895440

U2AFM
U2 small nuclear ribonucleoprotein auxiliary factor 35 kDa subunit-related protein 2

3

0

High-throughput

0.347

High

895447

PXDC2
Plexin domain-containing protein 2

2

0

High-throughput

0.328

High

66358

PRR19
Proline-rich protein 19

1

0

High-throughput

0.279

Low

278481

VAMP4
Vesicle-associated membrane protein 4

1

0

High-throughput

0.279

Low

337923

SIX6
Homeobox protein SIX6

1

0

High-throughput

0.279

Low

895454

ABCA9
ATP-binding cassette sub-family A member 9

1

0

High-throughput

0.279

Low

895459

ZN675
Zinc finger protein 675

1

0

High-throughput

0.279

Low

895473

SSRG
Translocon-associated protein subunit gamma

1

0

High-throughput

0.269

Low

84335

B6ZDN3
Doublecortin domain containing 1

1

0

High-throughput

0.249

Low

895437

RM49
Large ribosomal subunit protein mL49

1

0

High-throughput

0.232

Low

895462

FACOS
FANCD2 opposite strand protein

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025