Protein: SPB7
Serpin B7 (Megsin) (TP55)

Gene: SPB7, SERPINB7
Organism: Homo sapiens
Interactions: 70
UniProt ID: O75635

Gene Ontology (top 5):
GO:0004867 - serine-type endopeptidase inhibitor activity
GO:0005615 - extracellular space
GO:0005737 - cytoplasm
GO:0032914 - positive regulation of transforming growth factor beta1 production
GO:0032967 - positive regulation of collagen biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

289287

PLK2
Serine/threonine-protein kinase PLK2

3

3

High-throughput

0.667

High

289237

FRIH
Ferritin heavy chain

2

5

High-throughput

0.628

High

289244

GDF5
Growth/differentiation factor 5

2

8

High-throughput

0.628

High

289276

CDK15
Cyclin-dependent kinase 15

2

7

High-throughput

0.628

High

289263

TRI67
Tripartite motif-containing protein 67

1

13

High-throughput

0.618

High

289254

MCL1
Induced myeloid leukemia cell differentiation protein Mcl-1

2

3

High-throughput

0.611

High

289291

DD19B
ATP-dependent RNA helicase DDX19B

2

9

High-throughput

0.611

High

289255

KI3S1
Killer cell immunoglobulin-like receptor 3DS1

3

7

High-throughput

0.609

High

289256

NONO
Non-POU domain-containing octamer-binding protein

2

3

High-throughput

0.574

High

289285

TB22B
TBC1 domain family member 22B

2

7

High-throughput

0.574

High

289249

CF298
Cilia- and flagella-associated protein 298

2

4

High-throughput

0.558

High

289232

RENR
Renin receptor

1

6

High-throughput

0.536

High

289235

SG1D1
Secretoglobin family 1D member 1

1

5

High-throughput

0.536

High

289236

NUDT3
Diphosphoinositol polyphosphate phosphohydrolase 1

1

4

High-throughput

0.536

High

289238

IFNA4
Interferon alpha-4

1

2

High-throughput

0.536

High

289239

AATC
Aspartate aminotransferase, cytoplasmic

1

8

High-throughput

0.536

High

289242

CCR1
C-C chemokine receptor type 1

1

7

High-throughput

0.536

High

289251

SSBP2
Single-stranded DNA-binding protein 2

1

5

High-throughput

0.536

High

289281

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

7

High-throughput

0.536

High

289284

MBNL1
Muscleblind-like protein 1

1

5

High-throughput

0.536

High

289286

KLH11
Kelch-like protein 11

1

6

High-throughput

0.536

High

289288

HEY2
Hairy/enhancer-of-split related with YRPW motif protein 2

1

6

High-throughput

0.536

High

289294

SSUH2
Protein SSUH2 homolog

1

8

High-throughput

0.536

High

289295

RN115
E3 ubiquitin-protein ligase RNF115

1

7

High-throughput

0.536

High

289241

PURA2
Adenylosuccinate synthetase isozyme 2

1

0

High-throughput

0.513

High

185133

FANCG
Fanconi anemia group G protein

1

2

High-throughput

0.489

High

219786

CHSTA
Carbohydrate sulfotransferase 10

1

4

High-throughput

0.489

High

229195

G6PT1
Glucose-6-phosphate exchanger SLC37A4

1

4

High-throughput

0.489

High

252496

SEP15
Selenoprotein F

1

4

High-throughput

0.489

High

289234

OR2A4
Olfactory receptor 2A4

1

13

High-throughput

0.489

High

289240

CCNC
Cyclin-C

1

6

High-throughput

0.489

High

289245

KI67
Proliferation marker protein Ki-67

1

1

High-throughput

0.489

High

289247

STX17
Syntaxin-17

1

10

High-throughput

0.489

High

289248

DSCR6
Protein ripply3

1

7

High-throughput

0.489

High

289250

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

1

5

High-throughput

0.489

High

289252

GCYA1
Guanylate cyclase soluble subunit alpha-1

1

3

High-throughput

0.489

High

289253

GABPA
GA-binding protein alpha chain

1

6

High-throughput

0.489

High

289257

CR021
UPF0711 protein C18orf21

1

6

High-throughput

0.489

High

289259

VWA3B
von Willebrand factor A domain-containing protein 3B

1

1

High-throughput

0.489

High

289260

LRC10
Leucine-rich repeat-containing protein 10

1

4

High-throughput

0.489

High

289262

AMTN
Amelotin

1

1

High-throughput

0.489

High

289264

MOGT3
2-acylglycerol O-acyltransferase 3

1

7

High-throughput

0.489

High

289265

ZC3C1
Zinc finger C3HC-type protein 1

1

5

High-throughput

0.489

High

289266

AROS
Active regulator of SIRT1

1

2

High-throughput

0.489

High

289267

SFR1
Swi5-dependent recombination DNA repair protein 1 homolog

1

2

High-throughput

0.489

High

289268

EPHX4
Epoxide hydrolase 4

1

3

High-throughput

0.489

High

289271

RHBL4
Rhomboid-related protein 4

1

4

High-throughput

0.489

High

289272

ZDH19
Palmitoyltransferase ZDHHC19

1

3

High-throughput

0.489

High

289273

THAP4
Peroxynitrite isomerase THAP4

1

3

High-throughput

0.489

High

289274

PIGT
GPI-anchor transamidase component PIGT

1

4

High-throughput

0.489

High

289275

SARAF
Store-operated calcium entry-associated regulatory factor

1

9

High-throughput

0.489

High

289277

TEFM
Transcription elongation factor, mitochondrial

1

4

High-throughput

0.489

High

289279

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

7

High-throughput

0.489

High

289280

MMTA2
Multiple myeloma tumor-associated protein 2

1

5

High-throughput

0.489

High

289282

GALT9
Polypeptide N-acetylgalactosaminyltransferase 9

1

1

High-throughput

0.489

High

289283

TSSP
Thymus-specific serine protease

1

5

High-throughput

0.489

High

289290

PHF11
PHD finger protein 11

1

8

High-throughput

0.489

High

289292

PHF8
Histone lysine demethylase PHF8

1

3

High-throughput

0.489

High

289293

FOXJ3
Forkhead box protein J3

1

4

High-throughput

0.489

High

289233

CD123
Translation initiation factor eIF2 assembly protein

1

3

High-throughput

0.479

High

289246

SOX2
Transcription factor SOX-2

1

11

High-throughput

0.479

High

289278

RANB9
Ran-binding protein 9

1

5

Small-scale

0.479

High

289243

PI4KA
Phosphatidylinositol 4-kinase alpha

1

11

High-throughput

0.445

High

289261

OLFM4
Olfactomedin-4

1

3

High-throughput

0.445

High

289258

Q4LE69
Phosphatidylinositol 4-kinase alpha

1

11

High-throughput

0.437

High

219578

B2L11
Bcl-2-like protein 11

1

3

High-throughput

0.407

High

261020

NSMA
Sphingomyelin phosphodiesterase 2

1

8

High-throughput

0.407

High

289270

PI4P1
Putative inactive phosphatidylinositol 4-kinase alpha-like protein P1

1

11

High-throughput

0.407

High

289289

TCAL9
Transcription elongation factor A protein-like 9

1

2

High-throughput

0.407

High

289269

D106A
Beta-defensin 106

1

0

High-throughput

0.279

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025