HitPredict

Interactor 1: M3KCL (P57077)
MAP3K7 C-terminal-like protein (TAK1-like protein)
Gene: MAP3K7CL

Interactor 2: TAB3 (Q8N5C8)
TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 (Mitogen-activated protein kinase kinase kinase 7-interacting protein 3) (NF-kappa-B-activating protein 1) (TAK1-binding protein 3) (TAB-3) (TGF-beta-activated kinase 1-binding protein 3)
Gene: TAB3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.82	0.60	0.705

Property	Details
Experiments	25416956, 16189514, 32296183, unassigned1304
Identification Methods	two hybrid, validated two hybrid, two hybrid prey pooling approach, two hybrid array, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 142 Hs			1 712
+	Hs
		213967 M3K7_HUMAN (1-142): 8.63e-80: 248: 47.55		TAB3_HUMAN (1-712): 9.51e-99: 321: 100.00
+	Mm
		1201606 M3K7_MOUSE (1-142): 1e-79: 247: 47.55		TAB3_MOUSE (1-712): 3.82e-96: 314: 94.69
+	Hs
		214050 M3K7_HUMAN (1-142): 8.63e-80: 248: 47.55		TAB2_HUMAN (1-711): 5.01e-48: 182: 30.53
+	Rn
		505904 M3K7_RAT (1-142): 4.28e-81: 251: 47.55		TAB2_RAT (1-711): 1.27e-44: 172: 28.22
+	Mm
		1223486 M3K7_MOUSE (1-142): 1e-79: 247: 47.55		TAB2_MOUSE (1-711): 9.63e-45: 173: 29.44