Protein: TAB3
TGF-beta-activated kinase 1 and MAP3K7-binding protein 3 (Mitogen-activated protein kinase kinase kinase 7-interacting protein 3) (NF-kappa-B-activating protein 1) (TAK1-binding protein 3) (TAB-3) (TGF-beta-activated kinase 1-binding protein 3)

Gene: TAB3
Organism: Homo sapiens
Interactions: 66
UniProt ID: Q8N5C8

Gene Ontology (top 5):
GO:0005783 - endoplasmic reticulum
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0008270 - zinc ion binding
GO:0010008 - endosome membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

508275

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

7

12

Small-scale

0.962

High

213967

M3K7
Mitogen-activated protein kinase kinase kinase 7

22

6

Small-scale

0.767

High

1327563

TRAF6
TNF receptor-associated factor 6

7

17

Small-scale

0.743

High

1153068

TAB1
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1

6

1

Small-scale

0.735

High

943885

M3KCL
MAP3K7 C-terminal-like protein

4

5

High-throughput

0.705

High

1327558

TAB2
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2

3

15

Small-scale

0.662

High

1049555

1433F
14-3-3 protein eta

3

20

High-throughput

0.650

High

1126721

BECN1
Beclin-1

2

2

Small-scale

0.649

High

1327565

NEMO
NF-kappa-B essential modulator

2

15

Small-scale

0.629

High

1327564

EMIL1
EMILIN-1

2

16

High-throughput

0.628

High

1327560

UBQL2
Ubiquilin-2

1

3

High-throughput

0.618

High

1090784

TRAF2
TNF receptor-associated factor 2

2

13

Small-scale

0.601

High

142691

TRI38
E3 ubiquitin-protein ligase TRIM38

2

10

Small-scale

0.584

High

1327548

DC2I2
Cytoplasmic dynein 2 intermediate chain 2

1

16

Small-scale

0.573

High

1109322

PIN1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

1

2

High-throughput

0.573

High

378137

TNFA
Tumor necrosis factor

2

3

Small-scale

0.571

High

827844

STAT3
Signal transducer and activator of transcription 3

1

5

Small-scale

0.561

High

1327561

AMFR
E3 ubiquitin-protein ligase AMFR

1

4

Small-scale

0.561

High

132162

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

10

High-throughput

0.536

High

1315759

CE57L
Centrosomal protein CEP57L1

1

1

High-throughput

0.523

High

177696

SMAD7
Mothers against decapentaplegic homolog 7

1

3

Small-scale

0.515

High

1327553

HOIL1
RanBP-type and C3HC4-type zinc finger-containing protein 1

1

4

Small-scale

0.515

High

1327556

PPIL3
Peptidyl-prolyl cis-trans isomerase-like 3

1

4

Small-scale

0.512

High

185848

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

9

Small-scale

0.501

High

999540

NOMO3
BOS complex subunit NOMO3

1

1

High-throughput

0.489

High

167932

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

1

7

Small-scale

0.479

High

191226

TLR3
Toll-like receptor 3

1

4

Small-scale

0.479

High

271545

ATG13
Autophagy-related protein 13

1

1

Small-scale

0.479

High

349160

LATS1
Serine/threonine-protein kinase LATS1

1

3

High-throughput

0.479

High

350071

SNAI1
Zinc finger protein SNAI1

1

2

High-throughput

0.479

High

396507

ESR1
Estrogen receptor

1

20

Small-scale

0.479

High

572071

TRI27
Zinc finger protein RFP

1

11

Small-scale

0.479

High

691243

1433T
14-3-3 protein theta

1

20

High-throughput

0.479

High

730768

1433S
14-3-3 protein sigma

1

20

High-throughput

0.479

High

833000

ETV6
Transcription factor ETV6

1

15

High-throughput

0.479

High

862295

YAP1
Transcriptional coactivator YAP1

1

18

Small-scale

0.479

High

947225

NLRP6
NACHT, LRR and PYD domains-containing protein 6

1

5

Small-scale

0.479

High

966609

1433G
14-3-3 protein gamma

1

20

High-throughput

0.479

High

970774

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

5

High-throughput

0.479

High

971779

1433E
14-3-3 protein epsilon

1

3

Small-scale

0.479

High

990497

1433Z
14-3-3 protein zeta/delta

1

20

High-throughput

0.479

High

994657

YBOX1
Y-box-binding protein 1

1

4

Small-scale

0.479

High

1004824

RNF4
E3 ubiquitin-protein ligase RNF4

1

3

Small-scale

0.479

High

1095709

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

9

Small-scale

0.479

High

1128780

NBR1
Next to BRCA1 gene 1 protein

1

1

Small-scale

0.479

High

1161540

IF16
Gamma-interferon-inducible protein 16

1

4

High-throughput

0.479

High

1228994

RNF43
E3 ubiquitin-protein ligase RNF43

1

6

High-throughput

0.479

High

1327543

TAB3
TGF-beta-activated kinase 1 and MAP3K7-binding protein 3

1

14

Small-scale

0.479

High

1327544

BICD2
Protein bicaudal D homolog 2

1

18

High-throughput

0.479

High

1327545

AKAP1
A-kinase anchor protein 1, mitochondrial

1

1

High-throughput

0.479

High

1327546

PBIP1
Pre-B-cell leukemia transcription factor-interacting protein 1

1

1

Small-scale

0.479

High

1327547

RNF31
E3 ubiquitin-protein ligase RNF31

1

14

High-throughput

0.479

High

1327549

BICD1
Protein bicaudal D homolog 1

1

12

High-throughput

0.479

High

1327550

SNX27
Sorting nexin-27

1

12

High-throughput

0.479

High

1327551

ANM1
Protein arginine N-methyltransferase 1

1

9

High-throughput

0.479

High

1327552

CAR11
Caspase recruitment domain-containing protein 11

1

3

Small-scale

0.479

High

1327554

TRIM5
Tripartite motif-containing protein 5

1

10

Small-scale

0.479

High

1327555

WWTR1
WW domain-containing transcription regulator protein 1

1

16

High-throughput

0.479

High

1327557

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

3

High-throughput

0.479

High

1327559

ZRAN1
Ubiquitin thioesterase ZRANB1

1

14

High-throughput

0.479

High

1327562

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

4

Small-scale

0.479

High

410941

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

19

High-throughput

0.445

High

530079

TAU
Microtubule-associated protein tau

1

20

High-throughput

0.445

High

294014

CD123
Translation initiation factor eIF2 assembly protein

1

3

High-throughput

0.437

High

341623

EYA4
Protein phosphatase EYA4

1

16

High-throughput

0.437

High


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Last updated: 11Aug2025