HitPredict

Interactor 1: MAP1A (P78559)
Microtubule-associated protein 1A (MAP-1A) (Proliferation-related protein p80) [Cleaved into: MAP1A heavy chain; MAP1 light chain LC2]
Gene: MAP1A

Interactor 2: MLP3B (Q9GZQ8)
Microtubule-associated proteins 1A/1B light chain 3B (Autophagy-related protein LC3 B) (Autophagy-related ubiquitin-like modifier LC3 B) (MAP1 light chain 3-like protein 2) (MAP1A/MAP1B light chain 3 B) (MAP1A/MAP1B LC3 B) (Microtubule-associated protein 1 light chain 3 beta)
Gene: MAP1LC3B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.60	0.691

Property	Details
Experiments	31006538, 35271311, 20562859, 18083104
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005874 - microtubule GO:0008017 - microtubule binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2803 Hs			1 125
+	Hs
		944705 MAP1A_HUMAN (1-2803): 0: 1029: 100.00		MLP3A_HUMAN (1-120): 8.21e-55: 168: 82.50
+	Mm
		1265089 MAP1A_MOUSE (1-2803): 0: 905: 77.16		MLP3A_MOUSE (1-120): 8.21e-55: 168: 82.50
+	Hs
		807833 MAP1B_HUMAN (886-2803): 6.87e-73: 275: 15.16		MLP3B_HUMAN (1-125): 8.28e-57: 173: 100.00
+	Mm
		541479 MAP1B_MOUSE (857-2803): 1.39e-73: 277: 15.77		MLP3A_MOUSE (1-120): 8.21e-55: 168: 82.50
+	Hs
		807840 MAP1B_HUMAN (886-2803): 6.87e-73: 275: 15.16		MLP3A_HUMAN (1-120): 8.21e-55: 168: 82.50
+	Hs
		807660 MAP1B_HUMAN (886-2803): 6.87e-73: 275: 15.16		GBRL2_HUMAN (7-120): 2.21e-53: 165: 39.47
+	Hs
		518927 TPR_HUMAN (401-2740): 1.55e-57: 224: 8.84		MLP3A_HUMAN (1-120): 8.21e-55: 168: 82.50
+	Hs
		1146243 MAP1S_HUMAN (2163-2803): 4.97e-43: 175: 20.56		MLP3B_HUMAN (1-125): 8.28e-57: 173: 100.00
+	Hs
		1146245 MAP1S_HUMAN (2163-2803): 4.97e-43: 175: 20.56		MLP3A_HUMAN (1-120): 8.21e-55: 168: 82.50
+	Hs
		1051455 DCTN1_HUMAN (1206-1677): 2.47e-36: 153: 16.80		MLP3B_HUMAN (1-125): 8.28e-57: 173: 100.00
+	Hs
		1264799 TITIN_HUMAN (139-1866): 7.45e-22: 107: 10.64		MLP3B_HUMAN (1-125): 8.28e-57: 173: 100.00
+	Hs
		1264804 TITIN_HUMAN (139-1866): 7.45e-22: 107: 10.64		MLP3A_HUMAN (1-120): 8.21e-55: 168: 82.50
+	Hs
		891249 TITIN_HUMAN (139-1866): 7.45e-22: 107: 10.64		GBRL2_HUMAN (7-120): 2.21e-53: 165: 39.47
+	Hs
		1326218 SRRM2_HUMAN (1736-2728): 3.76e-19: 98: 10.66		MLP3B_HUMAN (1-125): 8.28e-57: 173: 100.00
+	Hs
		306254 TITIN_HUMAN (139-1866): 7.45e-22: 107: 10.64		GBRAP_HUMAN (7-121): 6.4e-53: 163: 31.30
+	Hs
		1264802 TITIN_HUMAN (139-1866): 7.45e-22: 107: 10.64		GBRL1_HUMAN (7-120): 1.5e-51: 160: 32.46
+	Hs
		1330674 SRRM2_HUMAN (1736-2728): 3.76e-19: 98: 10.66		MLP3A_HUMAN (1-120): 8.21e-55: 168: 82.50
+	Hs
		306357 SRRM2_HUMAN (1736-2728): 3.76e-19: 98: 10.66		GBRAP_HUMAN (7-121): 6.4e-53: 163: 31.30
+	Hs
		1326233 PRC2C_HUMAN (861-2729): 1.2e-11: 73.4: 7.65		MLP3B_HUMAN (1-125): 8.28e-57: 173: 100.00
+	Hs
		1328077 PRC2C_HUMAN (861-2729): 1.2e-11: 73.4: 7.65		GBRL1_HUMAN (7-120): 1.5e-51: 160: 32.46