Interactor 1: CBX1 (P83916)
Chromobox protein homolog 1 (HP1Hsbeta) (Heterochromatin protein 1 homolog beta) (HP1 beta) (Heterochromatin protein p25) (M31) (Modifier 1 protein) (p25beta)
Gene: CBX1

Interactor 2: DNM3A (Q9Y6K1)
DNA (cytosine-5)-methyltransferase 3A (Dnmt3a) (EC 2.1.1.37) (Cysteine methyltransferase DNMT3A) (EC 2.1.1.-) (DNA methyltransferase HsaIIIA) (DNA MTase HsaIIIA) (M.HsaIIIA)
Gene: DNMT3A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 12711675
Identification Methods pull down
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Chromo~DNA_methylase
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000775 - chromosome, centromeric region
GO:0000792 - heterochromatin
GO:0003682 - chromatin binding
GO:0005634 - nucleus
and 1 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 185
Hs

1 912
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024