HitPredict

Interactor 1: ARF1 (P84077)
ADP-ribosylation factor 1 (EC 3.6.5.2)
Gene: ARF1

Interactor 2: ARFG2 (Q8N6H7)
ADP-ribosylation factor GTPase-activating protein 2 (ARF GAP 2) (GTPase-activating protein ZNF289) (Zinc finger protein 289)
Gene: ARFGAP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35844135
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Arf~ArfGap
Common GO terms	GO:0000139 - Golgi membrane GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 181 Hs			1 521
+	Hs
		574712 ARF4_HUMAN (1-180): 1.54e-69: 210: 80.56		ARFG2_HUMAN (1-521): 3.38e-168: 487: 100.00
+	Hs
		950654 ARF5_HUMAN (1-180): 2.95e-68: 207: 80.56		ARFG2_HUMAN (1-521): 3.38e-168: 487: 100.00
+	Hs
		897383 ARF3_HUMAN (1-181): 6.38e-68: 206: 96.13		ARFG2_HUMAN (1-521): 3.38e-168: 487: 100.00
+	Hs
		574756 ARF4_HUMAN (1-180): 1.54e-69: 210: 80.56		ARFG3_HUMAN (3-520): 6.07e-131: 392: 53.80
+	Hs
		950718 ARF5_HUMAN (1-180): 2.95e-68: 207: 80.56		ARFG3_HUMAN (3-520): 6.07e-131: 392: 53.80
+	Hs
		897406 ARF3_HUMAN (1-181): 6.38e-68: 206: 96.13		ARFG3_HUMAN (3-520): 6.07e-131: 392: 53.80
+	Hs
		950563 ARF1_HUMAN (1-181): 5.85e-68: 206: 100.00		ARFG3_HUMAN (3-520): 6.07e-131: 392: 53.80
+	Hs
		913202 ARF6_HUMAN (5-179): 2.19e-73: 219: 68.00		GIT1_HUMAN (18-454): 3.31e-66: 229: 13.68
+	Hs
		950582 ARF1_HUMAN (1-181): 5.85e-68: 206: 100.00		GIT1_HUMAN (18-454): 3.31e-66: 229: 13.68
+	Hs
		912985 ARF6_HUMAN (5-179): 2.19e-73: 219: 68.00		SMAP1_HUMAN (3-422): 1.15e-61: 211: 16.74
+	Ce
		1353616 Q9U2S4_CAEEL (12-178): 2.07e-86: 253: 69.46		CNT1_CAEEL (12-217): 1.79e-44: 169: 24.16
+	Hs
		897381 ARF3_HUMAN (1-181): 6.38e-68: 206: 96.13		SMAP1_HUMAN (3-422): 1.15e-61: 211: 16.74
+	Hs
		950523 ARF1_HUMAN (1-181): 5.85e-68: 206: 100.00		ARFG1_HUMAN (6-387): 1.44e-62: 211: 21.66
+	Hs
		574718 ARF4_HUMAN (1-180): 1.54e-69: 210: 80.56		SMAP2_HUMAN (1-396): 1.69e-56: 196: 16.63
+	Hs
		897390 ARF3_HUMAN (1-181): 6.38e-68: 206: 96.13		SMAP2_HUMAN (1-396): 1.69e-56: 196: 16.63
+	Hs
		912909 ARF6_HUMAN (5-179): 2.19e-73: 219: 68.00		ACAP1_HUMAN (1-238): 1.58e-47: 177: 21.76
+	Hs
		912911 ARF6_HUMAN (5-179): 2.19e-73: 219: 68.00		ACAP2_HUMAN (2-250): 2.24e-47: 177: 19.05
+	At
		285978 ARF2B_ARATH (1-177): 7.31e-67: 203: 90.40		AGD7_ARATH (11-404): 4.33e-47: 171: 20.37
+	Hs
		913191 ARF6_HUMAN (5-179): 2.19e-73: 219: 68.00		AGAP1_HUMAN (6-136): 5.53e-36: 144: 27.48
+	Hs
		950579 ARF1_HUMAN (1-181): 5.85e-68: 206: 100.00		AGAP1_HUMAN (6-136): 5.53e-36: 144: 27.48