Protein: LCE2D
Late cornified envelope protein 2D (Late envelope protein 12) (Small proline-rich-like epidermal differentiation complex protein 1A)

Gene: LCE2D
Organism: Homo sapiens
Interactions: 75
UniProt ID: Q5TA82

Gene Ontology (top 5):
GO:0031424 - keratinization

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

950791

KR109
Keratin-associated protein 10-9

4

20

High-throughput

0.639

High

221367

SPY1
Protein sprouty homolog 1

4

4

High-throughput

0.637

High

950523

KR108
Keratin-associated protein 10-8

3

20

High-throughput

0.616

High

1215217

ATL4
ADAMTS-like protein 4

3

2

High-throughput

0.616

High

1215226

KR412
Keratin-associated protein 4-12

3

20

High-throughput

0.616

High

1215209

LCE2D
Late cornified envelope protein 2D

2

5

High-throughput

0.613

High

159065

LCE2B
Late cornified envelope protein 2B

2

2

High-throughput

0.606

High

1186630

KRA62
Keratin-associated protein 6-2

2

1

High-throughput

0.606

High

1213898

LCE1C
Late cornified envelope protein 1C

2

8

High-throughput

0.606

High

1213940

LCE1D
Late cornified envelope protein 1D

2

2

High-throughput

0.606

High

1214020

LCE1F
Late cornified envelope protein 1F

2

2

High-throughput

0.606

High

1214257

LCE1A
Late cornified envelope protein 1A

2

2

High-throughput

0.606

High

1214300

LCE1B
Late cornified envelope protein 1B

2

5

High-throughput

0.606

High

1215166

LCE2C
Late cornified envelope protein 2C

2

5

High-throughput

0.606

High

300162

GLRX3
Glutaredoxin-3

2

1

High-throughput

0.583

High

733163

OTX1
Homeobox protein OTX1

2

2

High-throughput

0.583

High

1215219

NT2NA
Notch homolog 2 N-terminal-like protein A

2

5

High-throughput

0.578

High

70271

CRTP1
Cysteine-rich tail protein 1

2

2

High-throughput

0.553

High

165181

TSN4
Tetraspanin-4

2

1

High-throughput

0.553

High

192095

PA2GX
Group 10 secretory phospholipase A2

2

1

High-throughput

0.553

High

685877

KRA59
Keratin-associated protein 5-9

2

20

High-throughput

0.553

High

705393

GRN
Progranulin

2

1

High-throughput

0.553

High

885285

HXA1
Homeobox protein Hox-A1

2

2

High-throughput

0.553

High

892212

MCSP
Sperm mitochondrial-associated cysteine-rich protein

2

1

High-throughput

0.553

High

949564

KR123
Keratin-associated protein 12-3

2

5

High-throughput

0.553

High

950169

KR106
Keratin-associated protein 10-6

2

20

High-throughput

0.553

High

1004684

RNF4
E3 ubiquitin-protein ligase RNF4

2

2

High-throughput

0.553

High

1059660

KRA11
Keratin-associated protein 1-1

2

20

High-throughput

0.553

High

1180100

VWC2
Brorin

2

1

High-throughput

0.553

High

1215212

VASN
Vasorin

2

2

High-throughput

0.553

High

1215213

KRA57
Keratin-associated protein 5-7

2

20

High-throughput

0.553

High

1215214

KRA56
Keratin-associated protein 5-6

2

2

High-throughput

0.553

High

1215218

KRA52
Keratin-associated protein 5-2

2

2

High-throughput

0.553

High

1215220

NUFP2
FMR1-interacting protein NUFIP2

2

2

High-throughput

0.553

High

1215221

KRA13
Keratin-associated protein 1-3

2

20

High-throughput

0.553

High

1215222

TRI42
Tripartite motif-containing protein 42

2

2

High-throughput

0.553

High

1215223

S39A7
Zinc transporter SLC39A7

2

1

High-throughput

0.553

High

1215224

NR4A3
Nuclear receptor subfamily 4 group A member 3

2

2

High-throughput

0.553

High

1215225

GUCD1
Protein GUCD1

2

1

High-throughput

0.553

High

1215228

KR171
Keratin-associated protein 17-1

2

2

High-throughput

0.553

High

1215229

KRA98
Keratin-associated protein 9-8

2

20

High-throughput

0.553

High

1215230

KRA93
Keratin-associated protein 9-3

2

20

High-throughput

0.553

High

1215233

KRA41
Keratin-associated protein 4-1

2

20

High-throughput

0.553

High

1215236

KRA42
Keratin-associated protein 4-2

2

20

High-throughput

0.553

High

1215238

KRA15
Keratin-associated protein 1-5

2

20

High-throughput

0.553

High

180536

PLS1
Phospholipid scramblase 1

1

2

High-throughput

0.523

High

221143

SPY2
Protein sprouty homolog 2

1

4

High-throughput

0.523

High

303150

RGS20
Regulator of G-protein signaling 20

1

4

High-throughput

0.523

High

351551

FBLN4
EGF-containing fibulin-like extracellular matrix protein 2

1

2

High-throughput

0.523

High

1212896

LCE3C
Late cornified envelope protein 3C

1

1

High-throughput

0.481

High

1213982

LCE1E
Late cornified envelope protein 1E

1

5

High-throughput

0.481

High

1215036

LCE3A
Late cornified envelope protein 3A

1

6

High-throughput

0.481

High

1215096

LCE4A
Late cornified envelope protein 4A

1

2

High-throughput

0.481

High

1215135

LCE2A
Late cornified envelope protein 2A

1

5

High-throughput

0.481

High

1215210

LCE5A
Late cornified envelope protein 5A

1

2

High-throughput

0.481

High

1215227

LCE3D
Late cornified envelope protein 3D

1

4

High-throughput

0.481

High

517030

NT2NC
Notch homolog 2 N-terminal-like protein C

1

5

High-throughput

0.470

High

950076

KR105
Keratin-associated protein 10-5

1

20

High-throughput

0.470

High

1215237

KRA24
Keratin-associated protein 2-4

1

20

High-throughput

0.470

High

545

NBPFJ
NBPF family member NBPF19

1

2

High-throughput

0.439

High

505338

KRA23
Keratin-associated protein 2-3

1

20

High-throughput

0.439

High

949717

KR101
Keratin-associated protein 10-1

1

20

High-throughput

0.439

High

950284

KR107
Keratin-associated protein 10-7

1

20

High-throughput

0.439

High

1215215

KRA54
Keratin-associated protein 5-4

1

20

High-throughput

0.439

High

1215216

KRA53
Keratin-associated protein 5-3

1

20

High-throughput

0.439

High

1215231

KRA92
Keratin-associated protein 9-2

1

20

High-throughput

0.439

High

1215232

KR411
Keratin-associated protein 4-11

1

20

High-throughput

0.439

High

1215234

KRA45
Keratin-associated protein 4-5

1

20

High-throughput

0.439

High

1215235

KRA44
Keratin-associated protein 4-4

1

20

High-throughput

0.439

High

452287

PDIA1
Protein disulfide-isomerase

2

0

High-throughput

0.316

High

962895

NCALD
Neurocalcin-delta

2

0

High-throughput

0.316

High

1186521

KR192
Keratin-associated protein 19-2

2

0

High-throughput

0.316

High

107808

SUMO5
Small ubiquitin-related modifier 5

1

0

High-throughput

0.268

Low

1215211

RN123
E3 ubiquitin-protein ligase RNF123

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025