Protein: LCE2B
Late cornified envelope protein 2B (Late envelope protein 10) (Skin-specific protein Xp5) (Small proline-rich-like epidermal differentiation complex protein 1B)

Gene: LCE2B
Organism: Homo sapiens
Interactions: 83
UniProt ID: O14633

Gene Ontology (top 5):
GO:0008544 - epidermis development
GO:0031424 - keratinization
GO:0042802 - identical protein binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

159036

KRA59
Keratin-associated protein 5-9

2

19

High-throughput

0.606

High

159054

LCE1C
Late cornified envelope protein 1C

2

2

High-throughput

0.606

High

159056

LCE1E
Late cornified envelope protein 1E

2

1

High-throughput

0.606

High

159059

LCE1B
Late cornified envelope protein 1B

2

1

High-throughput

0.606

High

159060

LCE3A
Late cornified envelope protein 3A

2

2

High-throughput

0.606

High

159063

LCE2A
Late cornified envelope protein 2A

2

1

High-throughput

0.606

High

159064

LCE2C
Late cornified envelope protein 2C

2

2

High-throughput

0.606

High

159065

LCE2D
Late cornified envelope protein 2D

2

2

High-throughput

0.606

High

159088

LCE3D
Late cornified envelope protein 3D

2

1

High-throughput

0.606

High

159047

KR109
Keratin-associated protein 10-9

3

18

High-throughput

0.597

High

159057

LCE1F
Late cornified envelope protein 1F

2

0

High-throughput

0.589

High

159027

LCE2B
Late cornified envelope protein 2B

2

0

High-throughput

0.580

High

159051

KRA62
Keratin-associated protein 6-2

2

0

High-throughput

0.580

High

159055

LCE1D
Late cornified envelope protein 1D

2

0

High-throughput

0.580

High

159058

LCE1A
Late cornified envelope protein 1A

2

0

High-throughput

0.580

High

159062

LCE4A
Late cornified envelope protein 4A

2

0

High-throughput

0.580

High

159066

LCE5A
Late cornified envelope protein 5A

2

0

High-throughput

0.580

High

159030

SPY3
Protein sprouty homolog 3

2

1

High-throughput

0.553

High

159031

RGS20
Regulator of G-protein signaling 20

2

1

High-throughput

0.553

High

159040

KR121
Keratin-associated protein 12-1

2

2

High-throughput

0.553

High

159041

KR122
Keratin-associated protein 12-2

2

20

High-throughput

0.553

High

159042

KR123
Keratin-associated protein 12-3

2

2

High-throughput

0.553

High

159045

KR107
Keratin-associated protein 10-7

2

15

High-throughput

0.553

High

159046

KR108
Keratin-associated protein 10-8

2

18

High-throughput

0.553

High

159050

KRA11
Keratin-associated protein 1-1

2

19

High-throughput

0.553

High

159068

KRA57
Keratin-associated protein 5-7

2

14

High-throughput

0.553

High

159077

SPRE2
Sprouty-related, EVH1 domain-containing protein 2

2

1

High-throughput

0.553

High

159079

KRA13
Keratin-associated protein 1-3

2

18

High-throughput

0.553

High

159081

NR4A3
Nuclear receptor subfamily 4 group A member 3

2

1

High-throughput

0.553

High

159087

KR412
Keratin-associated protein 4-12

2

20

High-throughput

0.553

High

159090

KRA98
Keratin-associated protein 9-8

2

20

High-throughput

0.553

High

159091

KRA93
Keratin-associated protein 9-3

2

20

High-throughput

0.553

High

159092

KRA92
Keratin-associated protein 9-2

2

20

High-throughput

0.553

High

159094

KRA45
Keratin-associated protein 4-5

2

20

High-throughput

0.553

High

159095

KRA44
Keratin-associated protein 4-4

2

20

High-throughput

0.553

High

159096

KRA42
Keratin-associated protein 4-2

2

20

High-throughput

0.553

High

159097

KRA33
Keratin-associated protein 3-3

2

1

High-throughput

0.553

High

159098

KRA31
Keratin-associated protein 3-1

2

1

High-throughput

0.553

High

159100

KRA15
Keratin-associated protein 1-5

2

19

High-throughput

0.553

High

159101

PLS4
Phospholipid scramblase 4

2

1

High-throughput

0.553

High

159102

PLS3
Phospholipid scramblase 3

2

1

High-throughput

0.553

High

159104

RGS17
Regulator of G-protein signaling 17

2

1

High-throughput

0.553

High

159052

KRA63
Keratin-associated protein 6-3

1

0

High-throughput

0.493

High

159035

NT2NC
Notch homolog 2 N-terminal-like protein C

1

1

High-throughput

0.483

High

159061

LCE3B
Late cornified envelope protein 3B

1

1

High-throughput

0.481

High

159083

Q96EJ4
PLAC8 protein

1

1

High-throughput

0.470

High

159099

KRA24
Keratin-associated protein 2-4

1

19

High-throughput

0.470

High

159053

LCE3C
Late cornified envelope protein 3C

1

0

High-throughput

0.460

High

159034

KRA23
Keratin-associated protein 2-3

1

19

High-throughput

0.439

High

159043

KR101
Keratin-associated protein 10-1

1

18

High-throughput

0.439

High

159044

KR106
Keratin-associated protein 10-6

1

15

High-throughput

0.439

High

159070

KRA54
Keratin-associated protein 5-4

1

11

High-throughput

0.439

High

159071

KRA53
Keratin-associated protein 5-3

1

14

High-throughput

0.439

High

159075

NT2NA
Notch homolog 2 N-terminal-like protein A

1

1

High-throughput

0.439

High

159093

KR411
Keratin-associated protein 4-11

1

20

High-throughput

0.439

High

159103

PLAC8
Placenta-specific gene 8 protein

1

1

High-throughput

0.439

High

159033

ESR1
Estrogen receptor

1

1

High-throughput

0.437

High

159029

PA2GX
Group 10 secretory phospholipase A2

2

0

High-throughput

0.320

High

159085

GUCD1
Protein GUCD1

2

0

High-throughput

0.320

High

159089

KR171
Keratin-associated protein 17-1

2

0

High-throughput

0.320

High

70035

CRTP1
Cysteine-rich tail protein 1

2

0

High-throughput

0.316

High

159028

TSN4
Tetraspanin-4

2

0

High-throughput

0.316

High

159032

TGFB1
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide

2

0

High-throughput

0.316

High

159037

GRN
Progranulin

2

0

High-throughput

0.316

High

159038

OTX1
Homeobox protein OTX1

2

0

High-throughput

0.316

High

159039

HXA1
Homeobox protein Hox-A1

2

0

High-throughput

0.316

High

159048

RNF4
E3 ubiquitin-protein ligase RNF4

2

0

High-throughput

0.316

High

159072

KR261
Keratin-associated protein 26-1

2

0

High-throughput

0.316

High

159073

ATL4
ADAMTS-like protein 4

2

0

High-throughput

0.316

High

159074

KRA52
Keratin-associated protein 5-2

2

0

High-throughput

0.316

High

159080

TRI42
Tripartite motif-containing protein 42

2

0

High-throughput

0.316

High

159082

NECT2
Nectin-2

2

0

High-throughput

0.316

High

159084

DHRS1
Dehydrogenase/reductase SDR family member 1

2

0

High-throughput

0.316

High

159086

MDFI
MyoD family inhibitor

2

0

High-throughput

0.316

High

159105

CRCT1
Cysteine-rich C-terminal protein 1

2

0

High-throughput

0.316

High

443

NBPFJ
NBPF family member NBPF19

1

0

High-throughput

0.251

Low

159067

VASN
Vasorin

1

0

High-throughput

0.251

Low

159069

KRA56
Keratin-associated protein 5-6

1

0

High-throughput

0.251

Low

159076

NUFP2
FMR1-interacting protein NUFIP2

1

0

High-throughput

0.251

Low

159078

KR111
Keratin-associated protein 11-1

1

0

High-throughput

0.251

Low

104831

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

159049

TF65
Transcription factor p65

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025