HitPredict

Interactor 1: RHOG (P84095)
Rho-related GTP-binding protein RhoG
Gene: RHOG

Interactor 2: CAV1 (Q03135)
Caveolin-1
Gene: CAV1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane GO:0005886 - plasma membrane GO:0005925 - focal adhesion GO:0019901 - protein kinase binding GO:0031410 - cytoplasmic vesicle and 1 others more... GO:1900027 - regulation of ruffle assembly
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 191 Hs			1 178
+	Hs
		925216 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		CAV1_HUMAN (1-178): 2.82e-109: 310: 100.00
+	Mm
		835141 RAC1_MOUSE (1-191): 3.6e-82: 243: 71.88		CAV1_MOUSE (1-178): 4.63e-108: 308: 94.94
+	Hs
		545335 RAC2_HUMAN (1-191): 1.28e-78: 234: 71.35		CAV1_HUMAN (1-178): 2.82e-109: 310: 100.00
+	Hs
		893921 CDC42_HUMAN (1-191): 1.3e-78: 234: 60.73		CAV1_HUMAN (1-178): 2.82e-109: 310: 100.00
+	Hs
		900399 RHOA_HUMAN (5-191): 1.26e-78: 234: 55.62		CAV1_HUMAN (1-178): 2.82e-109: 310: 100.00
+	Hs
		436263 RHOC_HUMAN (5-191): 8.34e-77: 230: 56.15		CAV1_HUMAN (1-178): 2.82e-109: 310: 100.00
+	Hs
		892328 RAC3_HUMAN (1-177): 1.67e-75: 226: 72.88		CAV1_HUMAN (1-178): 2.82e-109: 310: 100.00
+	Hs
		564489 RHOQ_HUMAN (4-189): 5.74e-73: 220: 56.84		CAV1_HUMAN (1-178): 2.82e-109: 310: 100.00
+	Hs
		848537 RHOG_HUMAN (1-191): 9.12e-82: 242: 100.00		CAV2_HUMAN (53-177): 5.1e-59: 183: 40.80