HitPredict

Interactor 1: RHOG (P84095)
Rho-related GTP-binding protein RhoG
Gene: RHOG

Interactor 2: RHG01 (Q07960)
Rho GTPase-activating protein 1 (CDC42 GTPase-activating protein) (GTPase-activating protein rhoGAP) (Rho-related small GTPase protein activator) (Rho-type GTPase-activating protein 1) (p50-RhoGAP)
Gene: ARHGAP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	31871319, 33513601
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Ras~RhoGAP
Common GO terms	GO:0005829 - cytosol GO:0007266 - Rho protein signal transduction GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 191 Hs			1 439
+	Hs
		925227 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		RHG01_HUMAN (1-439): 2.97e-164: 471: 100.00
+	Mm
		925791 RAC1_MOUSE (1-191): 3.6e-82: 243: 71.88		RHG01_MOUSE (1-439): 4.64e-163: 468: 96.58
+	Hs
		925343 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		RHG21_HUMAN (168-434): 3.18e-71: 246: 23.08
+	Hs
		925242 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		RHG05_HUMAN (148-435): 5.93e-67: 233: 20.85
+	Hs
		200213 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		SRGP3_HUMAN (182-434): 2.44e-66: 231: 26.44
+	Hs
		925319 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		RHG31_HUMAN (234-439): 3.47e-66: 231: 25.81
+	Hs
		925378 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		RHG27_HUMAN (208-432): 3.95e-67: 231: 23.14
+	Hs
		925394 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		RHG22_HUMAN (175-438): 7.18e-68: 230: 25.36
+	Mm
		925805 RAC1_MOUSE (1-191): 3.6e-82: 243: 71.88		RHG22_MOUSE (175-438): 2.95e-67: 229: 25.36
+	Hs
		925420 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		RHG12_HUMAN (196-432): 5.78e-66: 228: 22.92
+	Hs
		64688 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		RHG32_HUMAN (180-433): 7.32e-64: 225: 21.56
+	Hs
		147862 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		RHG33_HUMAN (164-438): 1.47e-63: 224: 22.38
+	Hs
		925329 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		RHG15_HUMAN (183-436): 1.02e-66: 222: 21.71
+	Mm
		925803 RAC1_MOUSE (1-191): 3.6e-82: 243: 71.88		RHG32_MOUSE (180-435): 3.64e-63: 222: 21.40
+	Hs
		551044 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		CHIN_HUMAN (187-431): 1.89e-66: 221: 21.51
+	Mm
		925802 RAC1_MOUSE (1-191): 3.6e-82: 243: 71.88		CHIO_MOUSE (187-431): 1.39e-67: 220: 21.91
+	Hs
		925395 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		SRGP1_HUMAN (220-432): 6.87e-62: 218: 26.24
+	Hs
		856140 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		CHIO_HUMAN (187-431): 1.49e-64: 216: 21.91
+	Hs
		302639 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		FA13A_HUMAN (242-431): 1.18e-25: 112: 34.03
+	Hs
		925354 RAC1_HUMAN (1-191): 3.6e-82: 243: 71.88		RHG17_HUMAN (242-405): 2.45e-19: 92.8: 32.73