HitPredict

Interactor 1: SRSF3 (P84103)
Serine/arginine-rich splicing factor 3 (Pre-mRNA-splicing factor SRP20) (Splicing factor, arginine/serine-rich 3)
Gene: SRSF3

Interactor 2: CHD4 (Q14839)
Chromodomain-helicase-DNA-binding protein 4 (CHD-4) (EC 3.6.4.12) (ATP-dependent helicase CHD4) (Mi-2 autoantigen 218 kDa protein) (Mi2-beta)
Gene: CHD4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	28977666
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PHD~RRM_1
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 164 Hs			1 1912
+	Hs
		1059643 SRSF7_HUMAN (9-106): 1.02e-30: 112: 67.35		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		992774 SRSF1_HUMAN (9-80): 1.1e-25: 100: 48.65		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		1028656 SRSF5_HUMAN (10-112): 2.09e-24: 97: 44.34		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		1031332 PABP4_HUMAN (5-91): 1.61e-21: 91.9: 26.09		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		516522 PABP1_HUMAN (1-91): 1.13e-20: 89.6: 25.77		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		1028548 SRSF9_HUMAN (9-82): 1.91e-19: 83.2: 40.79		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		1028915 SRSF6_HUMAN (11-88): 3.86e-16: 75.8: 47.44		CHD4_HUMAN (1-1912): 0: 1719: 100.00
+	Hs
		1018508 SRSF7_HUMAN (9-106): 1.02e-30: 112: 67.35		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		703377 CSTF2_HUMAN (10-110): 1.87e-25: 103: 25.47		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		951935 SRSF3_HUMAN (1-164): 6.39e-27: 100: 100.00		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		992741 SRSF1_HUMAN (9-80): 1.1e-25: 100: 48.65		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		1018454 SRSF5_HUMAN (10-112): 2.09e-24: 97: 44.34		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		1018458 PABP4_HUMAN (5-91): 1.61e-21: 91.9: 26.09		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		516483 PABP1_HUMAN (1-91): 1.13e-20: 89.6: 25.77		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Hs
		1018455 SRSF6_HUMAN (11-88): 3.86e-16: 75.8: 47.44		CHD3_HUMAN (23-1905): 0: 1595: 66.89
+	Dm
		332738 SRR55_DROME (11-89): 1.88e-16: 77: 46.84		CHDM_DROME (1-1904): 0: 1364: 50.85
+	Zm
		18681 A0A1D6H7I7_MAIZE (10-163): 3.59e-27: 105: 29.59		A0A1D6MT91_MAIZE (576-1632): 0: 764: 26.97
+	Dm
		1097620 RX21_DROME (10-81): 7.87e-22: 88.6: 54.17		ISWI_DROME (622-1638): 0: 770: 25.77
+	Hs
		516702 PABP1_HUMAN (1-91): 1.13e-20: 89.6: 25.77		CHD8_HUMAN (489-1678): 0: 752: 28.31
+	Hs
		151398 SRSF3_HUMAN (1-164): 6.39e-27: 100: 100.00		CHD1_HUMAN (491-1733): 0: 734: 27.99