HitPredict

Interactor 1: PP4C (P60510)
Serine/threonine-protein phosphatase 4 catalytic subunit (PP4C) (Pp4) (EC 3.1.3.16) (Protein phosphatase X) (PP-X)
Gene: PPP4C

Interactor 2: CCDC6 (Q16204)
Coiled-coil domain-containing protein 6 (Papillary thyroid carcinoma-encoded protein) (Protein H4)
Gene: CCDC6

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.93	0.60	0.750

Property	Details
Experiments	28514442, 33961781, 27880917, 17353931, 18715871, 19156129, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 307 Hs			1 474
+	Hs
		977502 PP2AB_HUMAN (6-307): 0: 525: 65.23		CCDC6_HUMAN (1-474): 6.19e-48: 173: 100.00
+	Hs
		994235 PP2AA_HUMAN (6-307): 0: 524: 65.89		CCDC6_HUMAN (1-474): 6.19e-48: 173: 100.00
+	Hs
		786626 PP1G_HUMAN (1-304): 0: 519: 43.81		CCDC6_HUMAN (1-474): 6.19e-48: 173: 100.00
+	Hs
		994436 PP2AA_HUMAN (6-307): 0: 524: 65.89		MRCKB_HUMAN (23-351): 3.72e-20: 96.2: 14.57
+	Hs
		786869 PP1G_HUMAN (1-304): 0: 519: 43.81		MYO5C_HUMAN (38-376): 2.2e-18: 90.8: 14.25
+	Hs
		967992 PP1A_HUMAN (2-304): 0: 517: 43.89		MYO5C_HUMAN (38-376): 2.2e-18: 90.8: 14.25
+	Hs
		772731 PP2AA_HUMAN (6-307): 0: 524: 65.89		MYH9_HUMAN (2-423): 5.53e-13: 73.9: 7.32
+	Hs
		772648 PP1G_HUMAN (1-304): 0: 519: 43.81		MYH9_HUMAN (2-423): 5.53e-13: 73.9: 7.32
+	Hs
		773149 PP2AB_HUMAN (6-307): 0: 525: 65.23		MYH10_HUMAN (3-329): 8.29e-11: 66.9: 13.46
+	Hs
		772713 PP1A_HUMAN (2-304): 0: 517: 43.89		MYH9_HUMAN (2-423): 5.53e-13: 73.9: 7.32
+	Hs
		977552 PP2AB_HUMAN (6-307): 0: 525: 65.23		CTTB2_HUMAN (49-216): 1.95e-09: 62.3: 10.06
+	Hs
		994315 PP2AA_HUMAN (6-307): 0: 524: 65.89		CTTB2_HUMAN (49-216): 1.95e-09: 62.3: 10.06
+	Mm
		968079 PP1A_MOUSE (2-304): 0: 518: 44.20		MYH6_MOUSE (36-399): 2.98e-10: 65: 11.56
+	Hs
		967887 PP1A_HUMAN (2-304): 0: 517: 43.89		MY18A_HUMAN (62-328): 1.49e-10: 65.8: 15.87
+	Hs
		786619 PP1G_HUMAN (1-304): 0: 519: 43.81		PLEC_HUMAN (67-346): 2.75e-09: 61.9: 11.79
+	Hs
		157030 PP1G_HUMAN (1-304): 0: 519: 43.81		CTRO_HUMAN (50-380): 3.18e-09: 61.6: 12.47
+	Hs
		157173 PP1A_HUMAN (2-304): 0: 517: 43.89		CTRO_HUMAN (50-380): 3.18e-09: 61.6: 12.47
+	Hs
		563003 PP1A_HUMAN (2-304): 0: 517: 43.89		MYH6_HUMAN (12-390): 5e-09: 61.2: 10.18