HitPredict

Interactor 1: SRSF3 (P84103)
Serine/arginine-rich splicing factor 3 (Pre-mRNA-splicing factor SRP20) (Splicing factor, arginine/serine-rich 3)
Gene: SRSF3

Interactor 2: FBW1A (Q9Y297)
F-box/WD repeat-containing protein 1A (E3RSIkappaB) (Epididymis tissue protein Li 2a) (F-box and WD repeats protein beta-TrCP) (pIkappaBalpha-E3 receptor subunit)
Gene: BTRC

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36199071
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 164 Hs			1 605
+	Hs
		1084454 SRSF7_HUMAN (9-106): 1.02e-30: 112: 67.35		FBW1A_HUMAN (1-605): 0: 551: 100.00
+	Hs
		992997 SRSF1_HUMAN (9-80): 1.1e-25: 100: 48.65		FBW1A_HUMAN (1-605): 0: 551: 100.00
+	Hs
		267101 SRS10_HUMAN (1-164): 2.25e-24: 96.6: 32.54		FBW1A_HUMAN (1-605): 0: 551: 100.00
+	Hs
		1031501 PABP4_HUMAN (5-91): 1.61e-21: 91.9: 26.09		FBW1A_HUMAN (1-605): 0: 551: 100.00
+	Hs
		1327900 CSTFT_HUMAN (10-110): 1.69e-24: 100: 24.53		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Hs
		1031492 PABP4_HUMAN (5-91): 1.61e-21: 91.9: 26.09		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Hs
		516733 PABP1_HUMAN (1-91): 1.13e-20: 89.6: 25.77		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Hs
		1084357 SRSF7_HUMAN (9-106): 1.02e-30: 112: 67.35		FBXW7_HUMAN (76-527): 7.38e-83: 276: 23.71
+	Hs
		992868 SRSF1_HUMAN (9-80): 1.1e-25: 100: 48.65		FBXW7_HUMAN (76-527): 7.38e-83: 276: 23.71
+	Hs
		1028761 SRSF5_HUMAN (10-112): 2.09e-24: 97: 44.34		FBXW7_HUMAN (76-527): 7.38e-83: 276: 23.71
+	Hs
		267038 SRS10_HUMAN (1-164): 2.25e-24: 96.6: 32.54		FBXW7_HUMAN (76-527): 7.38e-83: 276: 23.71
+	Hs
		952150 SRSF3_HUMAN (1-164): 6.39e-27: 100: 100.00		NLE1_HUMAN (33-408): 1.35e-41: 159: 13.21
+	Hs
		903258 SRSF7_HUMAN (9-106): 1.02e-30: 112: 67.35		WDR5_HUMAN (458-605): 5.01e-38: 145: 25.33
+	Hs
		1028844 SRSF5_HUMAN (10-112): 2.09e-24: 97: 44.34		NLE1_HUMAN (33-408): 1.35e-41: 159: 13.21
+	Hs
		903165 SRSF1_HUMAN (9-80): 1.1e-25: 100: 48.65		WDR5_HUMAN (458-605): 5.01e-38: 145: 25.33
+	Hs
		266949 SRS10_HUMAN (1-164): 2.25e-24: 96.6: 32.54		WDR5_HUMAN (458-605): 5.01e-38: 145: 25.33
+	Hs
		197006 SRSF1_HUMAN (9-80): 1.1e-25: 100: 48.65		PRP4_HUMAN (387-594): 6.19e-35: 140: 23.66
+	Hs
		903196 PABP4_HUMAN (5-91): 1.61e-21: 91.9: 26.09		WDR5_HUMAN (458-605): 5.01e-38: 145: 25.33
+	Hs
		516438 PABP1_HUMAN (1-91): 1.13e-20: 89.6: 25.77		WDR5_HUMAN (458-605): 5.01e-38: 145: 25.33
+	At
		58669 SR34A_ARATH (12-93): 1.2e-22: 93.2: 40.48		GBLPA_ARATH (439-584): 1.06e-09: 62.4: 31.21