HitPredict

Interactor 1: H33 (P84244)
Histone H3.3
Gene: H3-3a

Interactor 2: KDM6B (Q5NCY0)
Lysine-specific demethylase 6B (EC 1.14.11.68) (JmjC domain-containing protein 3) (Jumonji domain-containing protein 3) ([histone H3]-trimethyl-L-lysine(27) demethylase 6B)
Gene: KDM6B

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	17825402
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Mm			1 1641
+	Hs
		165840 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		KDM6B_HUMAN (1-1641): 0: 686: 89.01
+	Hs
		183098 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		KDM6A_HUMAN (1-630): 2.5e-83: 304: 16.18
+	Hs
		183122 H31T_HUMAN (1-136): 2.58e-59: 181: 93.38		KDM6A_HUMAN (1-630): 2.5e-83: 304: 16.18
+	Hs
		183127 H32_HUMAN (1-136): 5.32e-59: 180: 97.06		KDM6A_HUMAN (1-630): 2.5e-83: 304: 16.18
+	Hs
		934763 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		MDC1_HUMAN (144-1059): 1.17e-23: 111: 10.46
+	Hs
		952338 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		MDC1_HUMAN (144-1059): 1.17e-23: 111: 10.46
+	Hs
		935004 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		KMT2C_HUMAN (69-1237): 2.59e-16: 87.6: 9.52
+	Hs
		935440 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		CABIN_HUMAN (485-931): 4.46e-16: 86.8: 19.00
+	Hs
		952479 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		KMT2C_HUMAN (69-1237): 2.59e-16: 87.6: 9.52
+	Hs
		952733 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		CABIN_HUMAN (485-931): 4.46e-16: 86.8: 19.00
+	Hs
		1086228 H31T_HUMAN (1-136): 2.58e-59: 181: 93.38		KMT2C_HUMAN (69-1237): 2.59e-16: 87.6: 9.52
+	Hs
		934908 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		SRCAP_HUMAN (525-1188): 1.84e-11: 71.7: 12.46
+	Hs
		952426 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		SRCAP_HUMAN (525-1188): 1.84e-11: 71.7: 12.46
+	Mm
		101827 H33_MOUSE (1-136): 1.12e-59: 182: 100.00		F8WI37_MOUSE (749-1343): 2.26e-10: 68.4: 7.83
+	Hs
		152625 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		KMT2D_HUMAN (161-1356): 2.95e-09: 64.5: 8.58
+	Hs
		935150 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		MINT_HUMAN (171-770): 2.93e-09: 64.4: 12.64
+	Hs
		952573 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		MINT_HUMAN (171-770): 2.93e-09: 64.4: 12.64
+	Hs
		934872 H31_HUMAN (1-136): 3.08e-60: 183: 96.32		ARID2_HUMAN (155-1060): 7.95e-09: 62.9: 8.55
+	Hs
		952399 H33_HUMAN (1-136): 1.12e-59: 182: 100.00		ARID2_HUMAN (155-1060): 7.95e-09: 62.9: 8.55
+	Hs
		152661 H32_HUMAN (1-136): 5.32e-59: 180: 97.06		KMT2D_HUMAN (161-1356): 2.95e-09: 64.5: 8.58