HitPredict

Interactor 1: RAC3 (P60763)
Ras-related C3 botulinum toxin substrate 3 (EC 3.6.5.2) (p21-Rac3)
Gene: RAC3

Interactor 2: RFIP5 (Q9BXF6)
Rab11 family-interacting protein 5 (Rab11-FIP5) (Gamma-SNAP-associated factor 1) (Gaf-1) (Phosphoprotein pp75) (Rab11-interacting protein Rip11)
Gene: RAB11FIP5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RBD-FIP~Ras
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Hs			1 653
+	Hs
		988674 RAC1_HUMAN (1-192): 2.11e-85: 251: 92.71		RFIP5_HUMAN (1-653): 4.03e-162: 482: 100.00
+	Hs
		581266 RAC2_HUMAN (1-192): 9.15e-82: 242: 88.54		RFIP5_HUMAN (1-653): 4.03e-162: 482: 100.00
+	Hs
		1416776 RHOJ_HUMAN (2-190): 2.65e-80: 239: 60.32		RFIP5_HUMAN (1-653): 4.03e-162: 482: 100.00
+	Hs
		1015736 RHOG_HUMAN (1-192): 1.04e-78: 234: 69.79		RFIP5_HUMAN (1-653): 4.03e-162: 482: 100.00
+	Hs
		955547 CDC42_HUMAN (1-192): 1.05e-77: 231: 68.75		RFIP5_HUMAN (1-653): 4.03e-162: 482: 100.00
+	Ce
		145082 RAC1_CAEEL (1-192): 2.91e-83: 246: 81.25		UNC89_CAEEL (164-653): 4.55e-35: 145: 9.40
+	Hs
		319060 RAC1_HUMAN (1-192): 2.11e-85: 251: 92.71		K0754_HUMAN (146-604): 1.96e-33: 140: 9.61
+	Hs
		319049 RAC2_HUMAN (1-192): 9.15e-82: 242: 88.54		K0754_HUMAN (146-604): 1.96e-33: 140: 9.61
+	Hs
		319077 RHOJ_HUMAN (2-190): 2.65e-80: 239: 60.32		K0754_HUMAN (146-604): 1.96e-33: 140: 9.61
+	Hs
		319056 RAC3_HUMAN (1-192): 5.48e-80: 238: 100.00		K0754_HUMAN (146-604): 1.96e-33: 140: 9.61
+	Ce
		110130 G5EBV3_CAEEL (2-192): 1.3e-77: 231: 63.87		UNC89_CAEEL (164-653): 4.55e-35: 145: 9.40
+	Hs
		319064 RHOG_HUMAN (1-192): 1.04e-78: 234: 69.79		K0754_HUMAN (146-604): 1.96e-33: 140: 9.61
+	Hs
		319057 RHOA_HUMAN (5-192): 9.22e-77: 229: 55.32		K0754_HUMAN (146-604): 1.96e-33: 140: 9.61
+	Hs
		988461 RAC1_HUMAN (1-192): 2.11e-85: 251: 92.71		RFIP1_HUMAN (405-650): 1.83e-10: 66.4: 21.14
+	Hs
		581127 RAC2_HUMAN (1-192): 9.15e-82: 242: 88.54		RFIP1_HUMAN (405-650): 1.83e-10: 66.4: 21.14
+	Hs
		1250832 RHOJ_HUMAN (2-190): 2.65e-80: 239: 60.32		RFIP1_HUMAN (405-650): 1.83e-10: 66.4: 21.14
+	Hs
		953518 RAC3_HUMAN (1-192): 5.48e-80: 238: 100.00		RFIP1_HUMAN (405-650): 1.83e-10: 66.4: 21.14
+	Hs
		1015538 RHOG_HUMAN (1-192): 1.04e-78: 234: 69.79		RFIP1_HUMAN (405-650): 1.83e-10: 66.4: 21.14
+	Hs
		955309 CDC42_HUMAN (1-192): 1.05e-77: 231: 68.75		RFIP1_HUMAN (405-650): 1.83e-10: 66.4: 21.14
+	Hs
		962186 RHOA_HUMAN (5-192): 9.22e-77: 229: 55.32		RFIP1_HUMAN (405-650): 1.83e-10: 66.4: 21.14