HitPredict

Interactor 1: SNP25 (P60880)
Synaptosomal-associated protein 25 (SNAP-25) (Super protein) (SUP) (Synaptosomal-associated 25 kDa protein)
Gene: SNAP25

Interactor 2: STX12 (Q86Y82)
Syntaxin-12
Gene: STX12

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

Property	Details
Experiments	10886332, 30610939, unassigned3799
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005484 - SNAP receptor activity GO:0008021 - synaptic vesicle GO:0031201 - SNARE complex
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 206 Hs			1 276
+	Ce
		194911 O62414_CAEEL (1-203): 1.09e-64: 200: 52.20		STX1A_CAEEL (4-276): 2.42e-67: 212: 23.38
+	Mm
		204921 SNP25_MOUSE (1-206): 1.78e-64: 199: 100.00		STX1A_MOUSE (18-273): 2.44e-67: 212: 24.05
+	Rn
		746107 SNP25_RAT (1-206): 1.78e-64: 199: 100.00		STX1A_RAT (18-273): 3.24e-67: 212: 24.05
+	Hs
		954380 SNP25_HUMAN (1-206): 1.78e-64: 199: 100.00		STX1B_HUMAN (4-273): 3.81e-67: 212: 23.19
+	Rn
		954423 SNP25_RAT (1-206): 1.78e-64: 199: 100.00		STX1B_RAT (4-273): 3.81e-67: 212: 23.19
+	Bt
		746103 SNP25_BOVIN (1-206): 1.78e-64: 199: 100.00		STX1A_BOVIN (18-273): 1.1e-66: 211: 24.81
+	Hs
		954395 SNP25_HUMAN (1-206): 1.78e-64: 199: 100.00		STX1A_HUMAN (17-273): 6.84e-67: 211: 23.19
+	Hs
		746187 SNP25_HUMAN (1-206): 1.78e-64: 199: 100.00		STX2_HUMAN (16-272): 3.4e-66: 209: 26.62
+	Rn
		108160 SNP25_RAT (1-206): 1.78e-64: 199: 100.00		STX12_RAT (1-252): 1.73e-65: 207: 94.44
+	Dm
		788351 SNP25_DROME (4-204): 2.9e-62: 194: 60.89		STX1A_DROME (4-273): 6.42e-64: 204: 22.10
+	Rn
		894399 SNP25_RAT (1-206): 1.78e-64: 199: 100.00		STX2_RAT (16-252): 5.9e-59: 191: 25.10
+	Hs
		189488 SNP25_HUMAN (1-206): 1.78e-64: 199: 100.00		STX7_HUMAN (8-272): 1.12e-55: 181: 51.70
+	Hs
		954387 SNP25_HUMAN (1-206): 1.78e-64: 199: 100.00		STX4_HUMAN (6-272): 1.26e-53: 177: 24.27
+	Rn
		954429 SNP25_RAT (1-206): 1.78e-64: 199: 100.00		STX4_RAT (6-273): 2.16e-53: 177: 24.91
+	Hs
		954389 SNP25_HUMAN (1-206): 1.78e-64: 199: 100.00		STX3_HUMAN (5-250): 2.57e-53: 176: 25.20
+	Dm
		788353 SNP25_DROME (4-204): 2.9e-62: 194: 60.89		Q7K0X9_DROME (21-274): 3.76e-54: 178: 31.84
+	Rn
		954428 SNP25_RAT (1-206): 1.78e-64: 199: 100.00		STX3_RAT (5-250): 1.06e-51: 172: 25.60
+	Dm
		788364 SNP25_DROME (4-204): 2.9e-62: 194: 60.89		Q9VU45_DROME (13-269): 2.96e-49: 166: 28.41
+	Ce
		264318 O62414_CAEEL (1-203): 1.09e-64: 200: 52.20		STX3_CAEEL (22-269): 8.77e-44: 152: 20.64
+	Dm
		788362 SNP25_DROME (4-204): 2.9e-62: 194: 60.89		Q9VR90_DROME (166-256): 7.1e-11: 63.5: 36.26