HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: KSR2 (Q6VAB6)
Kinase suppressor of Ras 2 (hKSR2) (EC 2.7.11.1)
Gene: KSR2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 32707033
Identification Methods affinity chromatography technology, pull down
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PK_Tyr_Ser-Thr~Ras
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0043410 - positive regulation of MAPK cascade
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 191
Hs

1 950
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Service provided by Combinatics, Japan

Last updated: 11Aug2025