HitPredict

Interactor 1: CDC42 (P60953)
Cell division control protein 42 homolog (EC 3.6.5.2) (G25K GTP-binding protein)
Gene: CDC42

Interactor 2: SENP1 (Q9P0U3)
Sentrin-specific protease 1 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP1)
Gene: SENP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005925 - focal adhesion GO:0098978 - glutamatergic synapse
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 191 Hs			1 644
+	Hs
		1433551 RHOJ_HUMAN (2-188): 2.68e-85: 252: 64.17		SENP1_HUMAN (1-644): 0: 665: 100.00
+	Hs
		988778 RAC1_HUMAN (1-191): 1.15e-81: 242: 70.31		SENP1_HUMAN (1-644): 0: 665: 100.00
+	Hs
		1015869 RHOG_HUMAN (1-191): 7.33e-80: 237: 60.73		SENP1_HUMAN (1-644): 0: 665: 100.00
+	Hs
		962578 RHOA_HUMAN (5-191): 2.51e-78: 233: 53.48		SENP1_HUMAN (1-644): 0: 665: 100.00
+	Hs
		581343 RAC2_HUMAN (1-191): 1.01e-77: 232: 68.75		SENP1_HUMAN (1-644): 0: 665: 100.00
+	Hs
		953723 RAC3_HUMAN (1-177): 7.58e-76: 227: 72.32		SENP1_HUMAN (1-644): 0: 665: 100.00
+	Hs
		1015804 RHOG_HUMAN (1-191): 7.33e-80: 237: 60.73		SENP2_HUMAN (139-644): 1.49e-142: 429: 33.46
+	Hs
		955619 CDC42_HUMAN (1-191): 9.95e-80: 237: 100.00		SENP2_HUMAN (139-644): 1.49e-142: 429: 33.46
+	Hs
		962510 RHOA_HUMAN (5-191): 2.51e-78: 233: 53.48		SENP2_HUMAN (139-644): 1.49e-142: 429: 33.46
+	Hs
		581302 RAC2_HUMAN (1-191): 1.01e-77: 232: 68.75		SENP2_HUMAN (139-644): 1.49e-142: 429: 33.46
+	Hs
		466471 RHOC_HUMAN (5-191): 3.38e-76: 228: 52.41		SENP2_HUMAN (139-644): 1.49e-142: 429: 33.46