HitPredict

Interactor 1: DAB1 (P97318)
Disabled homolog 1
Gene: DAB1

Interactor 2: NCK1 (Q99M51)
SH2/SH3 adapter protein Nck1 (Cytoplasmic protein Nck1) (NCK adapter protein 1) (Nck-1)
Gene: NCK1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	15110774
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 588 Mm			1 377
+	Mm
		223010 DAB1_MOUSE (1-588): 2.98e-86: 281: 100.00		NCK2_MOUSE (1-376): 3.34e-90: 278: 67.19
+	Hs
		269120 DAB1_HUMAN (1-588): 1.81e-78: 260: 91.50		NCK1_HUMAN (1-377): 2.9e-97: 295: 98.94
+	Hs
		208964 DAB1_HUMAN (1-588): 1.81e-78: 260: 91.50		NCK2_HUMAN (1-376): 7.37e-90: 277: 68.50
+	Hs
		209098 ANS1B_HUMAN (8-229): 3.86e-44: 171: 16.81		NCK2_HUMAN (1-376): 7.37e-90: 277: 68.50
+	Mm
		763385 DAB1_MOUSE (1-588): 2.98e-86: 281: 100.00		FYN_MOUSE (6-130): 3.25e-22: 99.8: 21.26
+	Mm
		956225 DAB1_MOUSE (1-588): 2.98e-86: 281: 100.00		YES_MOUSE (5-130): 7.92e-22: 98.7: 20.31
+	Mm
		403429 DAB1_MOUSE (1-588): 2.98e-86: 281: 100.00		SRC_MOUSE (6-130): 5.82e-19: 90.1: 21.26
+	Hs
		269148 DAB1_HUMAN (1-588): 1.81e-78: 260: 91.50		ITSN1_HUMAN (1-127): 4.93e-15: 78.8: 15.75
+	Hs
		269176 DAB1_HUMAN (1-588): 1.81e-78: 260: 91.50		SH3K1_HUMAN (6-79): 2.48e-14: 76.2: 19.74
+	Hs
		655522 NUMBL_HUMAN (3-549): 2.08e-53: 193: 14.72		P85A_HUMAN (241-376): 2.35e-22: 100: 19.57
+	Dm
		112569 NUMB_DROME (16-521): 7.19e-45: 169: 13.48		M9ND00_DROME (17-267): 2.93e-22: 100: 19.57
+	Rn
		192744 SYNJ1_RAT (96-584): 4e-41: 162: 14.42		SRBS2_RAT (3-162): 7.67e-24: 105: 26.83
+	Dm
		957161 DAB_DROME (2-583): 9.69e-46: 176: 17.93		GRAP_DROME (1-61): 5.38e-17: 80.7: 31.15
+	Rn
		924995 SHC1_RAT (8-354): 9.65e-46: 169: 12.53		GRB2_RAT (3-58): 7.33e-17: 80.6: 28.57
+	Mm
		1206702 ANS1B_MOUSE (8-213): 6.78e-42: 164: 17.06		ITSN1_MOUSE (5-127): 9.02e-17: 84.3: 15.45
+	Mm
		403440 SHC3_MOUSE (9-373): 1.86e-41: 158: 14.43		SRC_MOUSE (6-130): 5.82e-19: 90.1: 21.26
+	Mm
		957157 DAB2_MOUSE (8-587): 2.89e-40: 158: 25.71		ITSN1_MOUSE (5-127): 9.02e-17: 84.3: 15.45
+	Hs
		1115812 Q49AR9_HUMAN (11-321): 2.68e-43: 164: 15.87		SH3K1_HUMAN (6-79): 2.48e-14: 76.2: 19.74
+	Mm
		957139 DAB2_MOUSE (8-587): 2.89e-40: 158: 25.71		GRB2_MOUSE (3-58): 7.7e-17: 80.6: 28.57
+	Mm
		957150 DAB2_MOUSE (8-587): 2.89e-40: 158: 25.71		SH3K1_MOUSE (58-209): 2.45e-11: 67.4: 18.18