HitPredict

Interactor 1: MAX (P61244)
Protein max (Class D basic helix-loop-helix protein 4) (bHLHd4) (Myc-associated factor X)
Gene: MAX

Interactor 2: RYBP (Q8N488)
RING1 and YY1-binding protein (Apoptin-associating protein 1) (APAP-1) (Death effector domain-associated factor) (DED-associated factor) (YY1 and E4TF1-associated factor 1)
Gene: RYBP

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	29028833, 27705803, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0045893 - positive regulation of DNA-templated transcription
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 160 Hs			1 228
+	Hs
		787879 SRBP1_HUMAN (9-149): 2.93e-25: 102: 20.00		RYBP_HUMAN (1-228): 2.8e-61: 193: 100.00
+	Hs
		959615 MAX_HUMAN (1-160): 2.06e-31: 112: 100.00		YAF2_HUMAN (3-227): 3.25e-55: 176: 52.89
+	Hs
		581690 MYOD1_HUMAN (11-151): 1.24e-24: 98.4: 16.33		YAF2_HUMAN (3-227): 3.25e-55: 176: 52.89
+	Hs
		372528 MYC_HUMAN (14-105): 1.82e-21: 91.5: 34.74		YAF2_HUMAN (3-227): 3.25e-55: 176: 52.89