HitPredict

Interactor 1: AP1M1 (Q00776)
AP-1 complex subunit mu-1-I (Clathrin assembly protein complex 1 mu-1-I medium chain) (Clathrin coat assembly protein AP54) (Clathrin coat-associated protein AP54) (Golgi adaptor AP-1 54 kDa protein) (HA1 54 kDa subunit) (Mu(1)-adaptin) (Mu1-I-adaptin)
Gene: APM1

Interactor 2: AP1G1 (Q12028)
AP-1 complex subunit gamma-1 (Clathrin assembly protein complex 1 gamma large chain) (Clathrin assembly protein large gamma chain) (Gamma-adaptin)
Gene: APL4

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.89 1.00 0.947

The method score is based on:

Property Details
Experiments 11805837, 16554755, 16429126, 37968396, 22940862, 34688652
Identification Methods anti tag coimmunoprecipitation, affinity chromatography technology, pull down, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Adap_comp_sub~Adaptin_N, Adaptin_N~Clat_adaptor_s
Common GO terms GO:0005829 - cytosol
GO:0006886 - intracellular protein transport
GO:0006896 - Golgi to vacuole transport
GO:0030121 - AP-1 adaptor complex
GO:0035615 - clathrin adaptor activity
and 1 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 475
Sc

1 832
+ Hs
+ Mm
+ Hs
+ At
+ Hs
+ At
+ Rn
+ Hs
+ Hs
+ Ce
+ Hs
+ Hs
+ Hs
+ Hs
+ At
+ At
+ Dm
+ At
+ At
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024