Interactor 1: MDM2 (Q00987)
E3 ubiquitin-protein ligase Mdm2 (EC 2.3.2.27) (Double minute 2 protein) (Hdm2) (Oncoprotein Mdm2) (RING-type E3 ubiquitin transferase Mdm2) (p53-binding protein Mdm2)
Gene: MDM2

Interactor 2: IFIX (Q6K0P9)
Pyrin and HIN domain-containing protein 1 (Interferon-inducible protein X)
Gene: PYHIN1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 0.60 0.584

The method score is based on:

Property Details
Experiments 16479015, 26186194
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0005829 - cytosol
GO:0031625 - ubiquitin protein ligase binding
GO:0031648 - protein destabilization
and 1 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 491
Hs

1 492
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024