Protein: BPL1
Biotin--protein ligase (EC 6.3.4.-) (Biotin apo-protein ligase) [Includes: Biotin--[methylmalonyl-CoA-carboxytransferase] ligase (EC 6.3.4.9); Biotin--[propionyl-CoA-carboxylase [ATP-hydrolyzing]] ligase (EC 6.3.4.10) (Holocarboxylase synthetase) (HCS); Biotin--[methylcrotonoyl-CoA-carboxylase] ligase (EC 6.3.4.11); Biotin--[acetyl-CoA-carboxylase] ligase (EC 6.3.4.15)]

Gene: BPL1, HLCS
Organism: Homo sapiens
Interactions: 36
UniProt ID: P50747

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0004077 - biotin-[acetyl-CoA-carboxylase] ligase activity
GO:0004078 - biotin-[methylcrotonoyl-CoA-carboxylase] ligase activity
GO:0004079 - biotin-[methylmalonyl-CoA-carboxytransferase] ligase activity
GO:0004080 - biotin-[propionyl-CoA-carboxylase (ATP-hydrolyzing)] ligase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

135995

ACACB
Acetyl-CoA carboxylase 2

1

0

Small-scale

0.726

High

841465

BPL1
Biotin--protein ligase

1

0

Small-scale

0.674

High

642027

KRA59
Keratin-associated protein 5-9

2

0

High-throughput

0.580

High

841466

RAB9A
Ras-related protein Rab-9A

2

0

High-throughput

0.547

High

841480

DUS15
Dual specificity protein phosphatase 15

1

1

High-throughput

0.536

High

841482

DUS22
Dual specificity protein phosphatase 22

1

1

High-throughput

0.536

High

841475

TP4A1
Protein tyrosine phosphatase type IVA 1

1

0

High-throughput

0.530

High

841478

SNX27
Sorting nexin-27

1

0

High-throughput

0.518

High

841479

QKI
KH domain-containing RNA-binding protein QKI

1

0

High-throughput

0.518

High

841481

SYSM
Serine--tRNA ligase, mitochondrial

1

0

High-throughput

0.518

High

841485

DDX52
Probable ATP-dependent RNA helicase DDX52

1

0

High-throughput

0.518

High

841467

CDKN3
Cyclin-dependent kinase inhibitor 3

1

0

High-throughput

0.513

High

64584

MYH7B
Myosin-7B

1

0

High-throughput

0.493

High

148052

DC1I1
Cytoplasmic dynein 1 intermediate chain 1

1

0

High-throughput

0.458

High

301683

TRI37
E3 ubiquitin-protein ligase TRIM37

1

0

High-throughput

0.458

High

418052

NPM
Nucleophosmin

1

0

High-throughput

0.458

High

552252

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

779034

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

823712

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.458

High

841470

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.458

High

841471

HOOK3
Protein Hook homolog 3

1

0

High-throughput

0.458

High

841484

DCTN4
Dynactin subunit 4

1

0

High-throughput

0.458

High

841468

SPT46
Spermatogenesis-associated protein 46

5

0

High-throughput

0.374

High

841469

TMC7
Transmembrane channel-like protein 7

2

0

High-throughput

0.328

High

841472

CTSRD
Cation channel sperm-associated auxiliary subunit delta

2

0

High-throughput

0.319

High

841476

TBC20
TBC1 domain family member 20

2

0

High-throughput

0.319

High

48636

MED19
Mediator of RNA polymerase II transcription subunit 19

2

0

High-throughput

0.316

High

841473

ANR29
Ankyrin repeat domain-containing protein 29

2

0

High-throughput

0.316

High

841483

POTE1
Protection of telomeres protein 1

1

0

High-throughput

0.296

High

841477

TXD15
Thioredoxin domain-containing protein 15

1

0

High-throughput

0.282

High

446018

CD63
CD63 antigen

1

0

High-throughput

0.279

Low

841474

THOC2
THO complex subunit 2

1

0

High-throughput

0.269

Low

319144

BRD1
Bromodomain-containing protein 1

1

0

High-throughput

0.249

Low

650695

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

719991

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024