HitPredict

Interactor 1: SODC (P61851)
Superoxide dismutase [Cu-Zn] (EC 1.15.1.1) (Superoxide dismutase 1)
Gene: Sod1

Interactor 2: THIO2 (Q9V429)
Thioredoxin-2 (DmTrx-2)
Gene: Trx2

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	22036573, 38944040
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006979 - response to oxidative stress GO:0008340 - determination of adult lifespan
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 153 Dm			1 106
+	At
		305856 SODC2_ARATH (4-151): 2.43e-68: 207: 56.00		TRXY2_ARATH (6-106): 2.94e-35: 119: 35.29
+	Hs
		361093 SODC_HUMAN (1-152): 8.08e-69: 206: 61.04		PDIA4_HUMAN (3-105): 4.83e-26: 102: 22.02
+	Hs
		361133 SODC_HUMAN (1-152): 8.08e-69: 206: 61.04		PDIA3_HUMAN (3-104): 3.22e-26: 102: 24.30
+	Mm
		1021767 CCS_MOUSE (4-149): 5.76e-61: 190: 44.60		THIOM_MOUSE (5-106): 1.29e-33: 115: 38.84
+	Hs
		361293 SODC_HUMAN (1-152): 8.08e-69: 206: 61.04		TXND2_HUMAN (8-102): 4.63e-19: 82.4: 46.32
+	Dm
		53773 A1Z850_DROME (8-149): 3.28e-48: 157: 43.15		THIO2_DROME (1-106): 1.89e-38: 126: 100.00
+	Mm
		148779 SODE_MOUSE (12-151): 5.56e-51: 164: 36.11		THIOM_MOUSE (5-106): 1.29e-33: 115: 38.84