HitPredict

Interactor 1: SRSF2 (Q01130)
Serine/arginine-rich splicing factor 2 (Protein PR264) (Splicing component, 35 kDa) (Splicing factor SC35) (SC-35) (Splicing factor, arginine/serine-rich 2)
Gene: SRSF2

Interactor 2: CUL5 (Q93034)
Cullin-5 (CUL-5) (Vasopressin-activated calcium-mobilizing receptor 1) (VACM-1)
Gene: CUL5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 221 Hs			1 780
+	Hs
		516626 PABP1_HUMAN (6-202): 1.69e-41: 150: 18.27		CUL5_HUMAN (1-780): 0: 792: 100.00
+	Hs
		1041638 SF3B4_HUMAN (4-205): 1.41e-52: 176: 17.24		CUL3_HUMAN (8-780): 0: 754: 22.96
+	Hs
		1040997 SF3B4_HUMAN (4-205): 1.41e-52: 176: 17.24		CUL1_HUMAN (11-780): 0: 748: 27.84
+	Hs
		516505 PABP1_HUMAN (6-202): 1.69e-41: 150: 18.27		CUL3_HUMAN (8-780): 0: 754: 22.96
+	Hs
		963981 SRSF2_HUMAN (1-221): 1.22e-43: 147: 100.00		CUL3_HUMAN (8-780): 0: 754: 22.96
+	Hs
		516503 PABP1_HUMAN (6-202): 1.69e-41: 150: 18.27		CUL1_HUMAN (11-780): 0: 748: 27.84
+	Hs
		1031416 PABP4_HUMAN (5-191): 4.16e-25: 104: 13.37		CUL5_HUMAN (1-780): 0: 792: 100.00
+	Hs
		963979 SRSF2_HUMAN (1-221): 1.22e-43: 147: 100.00		CUL1_HUMAN (11-780): 0: 748: 27.84
+	Hs
		516506 PABP1_HUMAN (6-202): 1.69e-41: 150: 18.27		CUL4A_HUMAN (16-780): 0: 744: 24.48
+	Hs
		1020253 ELAV2_HUMAN (1-195): 6.01e-38: 136: 15.79		CUL3_HUMAN (8-780): 0: 754: 22.96
+	Hs
		516507 PABP1_HUMAN (6-202): 1.69e-41: 150: 18.27		CUL4B_HUMAN (16-780): 0: 736: 25.39
+	Hs
		1031317 PABP4_HUMAN (5-191): 4.16e-25: 104: 13.37		CUL3_HUMAN (8-780): 0: 754: 22.96
+	Hs
		1042781 PUF60_HUMAN (8-108): 1.34e-23: 100: 23.76		CUL3_HUMAN (8-780): 0: 754: 22.96
+	Hs
		1031315 PABP4_HUMAN (5-191): 4.16e-25: 104: 13.37		CUL1_HUMAN (11-780): 0: 748: 27.84
+	Hs
		516504 PABP1_HUMAN (6-202): 1.69e-41: 150: 18.27		CUL2_HUMAN (6-780): 0: 699: 26.36
+	Hs
		1031318 PABP4_HUMAN (5-191): 4.16e-25: 104: 13.37		CUL4A_HUMAN (16-780): 0: 744: 24.48
+	Hs
		963980 SRSF2_HUMAN (1-221): 1.22e-43: 147: 100.00		CUL2_HUMAN (6-780): 0: 699: 26.36
+	Hs
		1031319 PABP4_HUMAN (5-191): 4.16e-25: 104: 13.37		CUL4B_HUMAN (16-780): 0: 736: 25.39
+	Hs
		680446 TIA1_HUMAN (9-184): 2.34e-16: 78.5: 10.67		CUL1_HUMAN (11-780): 0: 748: 27.84
+	Hs
		1031316 PABP4_HUMAN (5-191): 4.16e-25: 104: 13.37		CUL2_HUMAN (6-780): 0: 699: 26.36