HitPredict

Interactor 1: SUMO2 (P61956)
Small ubiquitin-related modifier 2 (SUMO-2) (HSMT3) (SMT3 homolog 2) (SUMO-3) (Sentrin-2) (Ubiquitin-like protein SMT3B) (Smt3B)
Gene: SUMO2

Interactor 2: RING2 (Q99496)
E3 ubiquitin-protein ligase RING2 (EC 2.3.2.27) (Huntingtin-interacting protein 2-interacting protein 3) (HIP2-interacting protein 3) (Protein DinG) (RING finger protein 1B) (RING1b) (RING finger protein 2) (RING finger protein BAP-1) (RING-type E3 ubiquitin transferase RING2)
Gene: RNF2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.60	0.457

Property	Details
Experiments	16169070
Identification Methods	two hybrid pooling approach
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 95 Hs			1 336
+	Hs
		765315 SUMO2_HUMAN (1-95): 3.58e-44: 139: 100.00		BMI1_HUMAN (34-332): 1.52e-45: 159: 15.51
+	Hs
		766075 SUMO3_HUMAN (1-94): 3.78e-41: 132: 96.81		PCGF2_HUMAN (34-332): 3.08e-44: 156: 16.89
+	Hs
		964253 SUMO2_HUMAN (1-95): 3.58e-44: 139: 100.00		TRI26_HUMAN (36-282): 2.85e-36: 139: 17.90
+	Hs
		798926 SUMO2_HUMAN (1-95): 3.58e-44: 139: 100.00		BRCA1_HUMAN (36-214): 1.16e-33: 133: 25.79
+	Hs
		991418 SUMO1_HUMAN (1-93): 7.79e-35: 116: 45.36		TRIM5_HUMAN (38-285): 7.02e-37: 140: 14.23
+	Hs
		798967 SUMO1_HUMAN (1-93): 7.79e-35: 116: 45.36		BRCA1_HUMAN (36-214): 1.16e-33: 133: 25.79
+	At
		846836 SUMO1_ARATH (1-91): 8.65e-36: 118: 47.25		COP1_ARATH (3-208): 3.85e-32: 128: 20.67