HitPredict

Interactor 1: ANK2 (Q01484)
Ankyrin-2 (ANK-2) (Ankyrin-B) (Brain ankyrin) (Non-erythroid ankyrin)
Gene: ANK2

Interactor 2: EHD2 (Q9NZN4)
EH domain-containing protein 2 (PAST homolog 2)
Gene: EHD2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	20489164
Identification Methods	pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005769 - early endosome GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0006897 - endocytosis GO:0072659 - protein localization to plasma membrane
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 3957 Hs			1 543
+	Hs
		965155 ANK2_HUMAN (1-3957): 0: 1910: 100.00		EHD1_HUMAN (1-538): 0: 820: 70.63
+	Hs
		965166 ANK2_HUMAN (1-3957): 0: 1910: 100.00		EHD3_HUMAN (1-540): 0: 800: 70.56
+	Hs
		965151 ANK2_HUMAN (1-3957): 0: 1910: 100.00		EHD4_HUMAN (1-543): 0: 795: 67.95
+	Mm
		1206516 ANK2_MOUSE (1-3957): 0: 1769: 80.90		EHD2_MOUSE (1-543): 0: 837: 96.69
+	Mm
		1208059 ANK2_MOUSE (1-3957): 0: 1769: 80.90		EHD1_MOUSE (1-538): 0: 819: 70.26
+	Mm
		1208055 ANK2_MOUSE (1-3957): 0: 1769: 80.90		EHD4_MOUSE (1-543): 0: 803: 67.95
+	Mm
		1208057 ANK2_MOUSE (1-3957): 0: 1769: 80.90		EHD3_MOUSE (1-540): 0: 793: 70.56
+	Hs
		787897 ANK2_HUMAN (1-3957): 0: 1910: 100.00		EPS15_HUMAN (451-541): 3.38e-13: 74.7: 26.09
+	Hs
		1331788 ANFY1_HUMAN (2-203): 1.72e-30: 135: 16.74		EHD1_HUMAN (1-538): 0: 820: 70.63
+	Hs
		1349321 ANFY1_HUMAN (2-203): 1.72e-30: 135: 16.74		EHD3_HUMAN (1-540): 0: 800: 70.56
+	Hs
		257713 ANR17_HUMAN (27-327): 1.68e-19: 99.8: 30.33		ITSN2_HUMAN (444-533): 3.82e-14: 77.8: 39.56
+	Hs
		1021469 ANK3_HUMAN (3120-3957): 1.41e-10: 70.3: 8.79		EP15R_HUMAN (453-541): 3.2e-09: 61.6: 27.78