HitPredict

Interactor 1: NC2B (Q01658)
Protein Dr1 (Down-regulator of transcription 1) (Negative cofactor 2-beta) (NC2-beta) (TATA-binding protein-associated phosphoprotein)
Gene: DR1

Interactor 2: KAT2A (Q92830)
Histone acetyltransferase KAT2A (EC 2.3.1.48) (General control of amino acid synthesis protein 5-like 2) (Histone acetyltransferase GCN5) (hGCN5) (Histone glutaryltransferase KAT2A) (EC 2.3.1.-) (Histone succinyltransferase KAT2A) (EC 2.3.1.-) (Lysine acetyltransferase 2A) (STAF97)
Gene: KAT2A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.78 0.60 0.686

The method score is based on:

Property Details
Experiments 24981860, 33961781, 18838386, 37682711
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005654 - nucleoplasm
GO:0006355 - regulation of DNA-templated transcription
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0045995 - regulation of embryonic development
and 5 others

more...
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 176
Hs

1 837
+ Mm
+ Hs
+ Hs
+ Dm
+ Dm
+ Dm
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024