Interactor 1: EXOSX (Q01780)
Exosome complex component 10 (EC 3.1.13.-) (Autoantigen PM/Scl 2) (P100 polymyositis-scleroderma overlap syndrome-associated autoantigen) (Polymyositis/scleroderma autoantigen 100 kDa) (PM/Scl-100) (Polymyositis/scleroderma autoantigen 2)
Gene: EXOSC10

Interactor 2: C1D (Q13901)
Nuclear nucleic acid-binding protein C1D (hC1D)
Gene: C1D

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.87 0.90 0.887

The method score is based on:

Property Details
Experiments 28514442, 33961781, 29395067, 37071682, 17412707
Identification Methods affinity chromatography technology, proximity labelling technology, cross-linking study, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, pull down
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains HRDC~Sas10_Utp3, PMC2NT~Sas10_Utp3
Common GO terms GO:0000176 - nuclear exosome (RNase complex)
GO:0000178 - exosome (RNase complex)
GO:0000460 - maturation of 5.8S rRNA
GO:0003723 - RNA binding
GO:0005634 - nucleus
and 3 others

more...

Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024