Interactor 1: PP1A (P62136)
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PP-1A) (EC 3.1.3.16)
Gene: PPP1CA

Interactor 2: PP1A (P62136)
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PP-1A) (EC 3.1.3.16)
Gene: PPP1CA

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.56 1.00 0.754

The method score is based on:

Property Details
Experiments 29669786, 31839598
Identification Methods affinity chromatography technology, cross-linking study
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Metallophos~Metallophos, Metallophos~STPPase_N, STPPase_N~STPPase_N
Common GO terms GO:0000164 - protein phosphatase type 1 complex
GO:0001111 - RNA polymerase II promoter clearance
GO:0004721 - phosphoprotein phosphatase activity
GO:0004722 - protein serine/threonine phosphatase activity
GO:0005506 - iron ion binding
and 40 others

more...

Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 330
Hs

1 330
+ Mm
+ Hs
+ Mm
+ Hs
+ Mm
+ Hs
+ Mm
+ Hs
+ Mm
+ Dm
+ Sc
+ Dm

Service provided by Combinatics, Japan

Last updated: 11Aug2025