Interactor 1: PP1G (P36873)
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit (PP-1G) (EC 3.1.3.16) (Protein phosphatase 1C catalytic subunit)
Gene: PPP1CC

Interactor 2: PP1A (P62136)
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (PP-1A) (EC 3.1.3.16)
Gene: PPP1CA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.980

The method score is based on:

Property Details
Experiments 28330616, 34349018, 36652389, 38334954, 26186194, 26496610, 28514442, 27173435, 30344098, 33961781, 35575683, 24366813
Identification Methods affinity chromatography technology, cross-linking study, proximity labelling technology, tandem affinity purification, pull down, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Metallophos~Metallophos, Metallophos~STPPase_N, STPPase_N~STPPase_N
Common GO terms GO:0004721 - phosphoprotein phosphatase activity
GO:0004722 - protein serine/threonine phosphatase activity
GO:0005634 - nucleus
GO:0005730 - nucleolus
GO:0005737 - cytoplasm
and 13 others

more...

Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 323
Hs

1 330
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Last updated: 11Aug2025