HitPredict

Interactor 1: MEF2A (Q02078)
Myocyte-specific enhancer factor 2A (Serum response factor-like protein 1)
Gene: MEF2A

Interactor 2: EP300 (Q09472)
Histone acetyltransferase p300 (p300 HAT) (EC 2.3.1.48) (E1A-associated protein p300) (Histone butyryltransferase p300) (EC 2.3.1.-) (Histone crotonyltransferase p300) (EC 2.3.1.-) (Protein 2-hydroxyisobutyryltransferase p300) (EC 2.3.1.-) (Protein lactyltransferas p300) (EC 2.3.1.-) (Protein propionyltransferase p300) (EC 2.3.1.-)
Gene: EP300

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.624

The method score is based on:

Property	Details
Experiments	12371907, 20590529
Identification Methods	pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0005654 - nucleoplasm and 7 others more... GO:0005667 - transcription regulator complex GO:0005829 - cytosol GO:0006915 - apoptotic process GO:0007507 - heart development GO:0045944 - positive regulation of transcription by RNA polymerase II GO:0061629 - RNA polymerase II-specific DNA-binding transcription factor binding GO:0140297 - DNA-binding transcription factor binding
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1	507
Hs

1	2414

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024