HitPredict

Interactor 1: GCYB1 (Q02153)
Guanylate cyclase soluble subunit beta-1 (GCS-beta-1) (EC 4.6.1.2) (Guanylate cyclase soluble subunit beta-3) (GCS-beta-3) (Soluble guanylate cyclase small subunit)
Gene: GUCY1B1

Interactor 2: ANKY2 (Q8IV38)
Ankyrin repeat and MYND domain-containing protein 2
Gene: ANKMY2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0046872 - metal ion binding
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 619 Hs			1 441
+	Hs
		969019 GCYA1_HUMAN (50-619): 0: 531: 33.96		ANKY2_HUMAN (1-441): 8.31e-108: 327: 100.00
+	Hs
		200747 ADCY6_HUMAN (183-609): 4.15e-78: 270: 19.48		ANKY2_HUMAN (1-441): 8.31e-108: 327: 100.00
+	Hs
		768546 ADCY8_HUMAN (262-610): 5.64e-66: 236: 22.53		ANKY2_HUMAN (1-441): 8.31e-108: 327: 100.00
+	Hs
		995732 ADCY2_HUMAN (250-617): 3.21e-63: 228: 20.00		ANKY2_HUMAN (1-441): 8.31e-108: 327: 100.00
+	Hs
		235387 ADCY9_HUMAN (375-601): 2.87e-56: 208: 27.12		ANKY2_HUMAN (1-441): 8.31e-108: 327: 100.00