HitPredict

Interactor 1: ID2 (Q02363)
DNA-binding protein inhibitor ID-2 (Class B basic helix-loop-helix protein 26) (bHLHb26) (Inhibitor of DNA binding 2) (Inhibitor of differentiation 2)
Gene: ID2

Interactor 2: OLIG1 (Q8TAK6)
Oligodendrocyte transcription factor 1 (Oligo1) (Class B basic helix-loop-helix protein 6) (bHLHb6) (Class E basic helix-loop-helix protein 21) (bHLHe21)
Gene: OLIG1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	15280210
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	HLH~HLH
Common GO terms	GO:0005634 - nucleus GO:0046983 - protein dimerization activity GO:0048663 - neuron fate commitment
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 134 Hs			1 271
+	Mm
		781011 ID2_MOUSE (1-134): 1.14e-70: 209: 98.51		OLIG1_MOUSE (1-271): 1.53e-54: 178: 82.29
+	Hs
		526743 ID2_HUMAN (1-134): 1.82e-70: 209: 100.00		MYF5_HUMAN (69-264): 1.29e-33: 124: 14.83
+	Hs
		970566 ID2_HUMAN (1-134): 1.82e-70: 209: 100.00		OLIG2_HUMAN (41-254): 4.45e-32: 122: 32.39
+	Mm
		781010 ID2_MOUSE (1-134): 1.14e-70: 209: 98.51		OLIG2_MOUSE (41-254): 2.08e-30: 117: 31.98
+	Hs
		814911 ID4_HUMAN (33-109): 7.03e-31: 109: 54.12		OLIG1_HUMAN (1-271): 2.16e-58: 189: 100.00
+	Mm
		781014 ID4_MOUSE (33-109): 1.73e-30: 108: 54.12		OLIG1_MOUSE (1-271): 1.53e-54: 178: 82.29
+	Hs
		526742 ID1_HUMAN (14-133): 1.58e-45: 146: 45.39		MYF5_HUMAN (69-264): 1.29e-33: 124: 14.83
+	Hs
		526744 ID3_HUMAN (1-133): 8.38e-44: 141: 39.13		MYF5_HUMAN (69-264): 1.29e-33: 124: 14.83
+	Hs
		546071 ID1_HUMAN (14-133): 1.58e-45: 146: 45.39		MYOG_HUMAN (32-236): 3.01e-30: 114: 16.67
+	Mm
		589139 ID1_MOUSE (15-123): 2.97e-41: 136: 50.00		TAL1_MOUSE (21-254): 2.09e-26: 107: 20.09
+	Hs
		814906 ID4_HUMAN (33-109): 7.03e-31: 109: 54.12		OLIG2_HUMAN (41-254): 4.45e-32: 122: 32.39
+	Mm
		781013 ID4_MOUSE (33-109): 1.73e-30: 108: 54.12		OLIG2_MOUSE (41-254): 2.08e-30: 117: 31.98
+	Hs
		546072 ID4_HUMAN (33-109): 7.03e-31: 109: 54.12		MYOG_HUMAN (32-236): 3.01e-30: 114: 16.67
+	Hs
		814916 ID4_HUMAN (33-109): 7.03e-31: 109: 54.12		NGN3_HUMAN (40-228): 1.5e-27: 107: 22.55
+	Hs
		568188 ID4_HUMAN (33-109): 7.03e-31: 109: 54.12		TAL1_HUMAN (17-254): 3.52e-26: 106: 18.33
+	Hs
		616610 ID4_HUMAN (33-109): 7.03e-31: 109: 54.12		MYF6_HUMAN (22-206): 9.62e-26: 103: 18.62