HitPredict

Interactor 1: HHEX (Q03014)
Hematopoietically-expressed homeobox protein HHEX (Homeobox protein HEX) (Homeobox protein PRH) (Proline-rich homeodomain protein)
Gene: HHEX

Interactor 2: ASPP2 (Q13625)
Apoptosis-stimulating of p53 protein 2 (Bcl2-binding protein) (Bbp) (Renal carcinoma antigen NY-REN-51) (Tumor suppressor p53-binding protein 2) (53BP2) (p53-binding protein 2) (p53BP2)
Gene: TP53BP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	32296183
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0042803 - protein homodimerization activity
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 270 Hs			1 1128
+	Hs
		974245 HHEX_HUMAN (1-270): 3.48e-55: 180: 100.00		Q05BL1_HUMAN (90-1128): 2.47e-152: 484: 99.90
+	Hs
		166890 HXA7_HUMAN (17-207): 6.19e-33: 121: 22.40		ANR28_HUMAN (771-1049): 2.48e-23: 109: 13.78
+	Hs
		568030 HXB6_HUMAN (41-213): 4.61e-35: 127: 26.46		ANKH1_HUMAN (922-1013): 2.42e-20: 100: 30.44
+	Hs
		453058 HXB7_HUMAN (16-207): 9.97e-33: 121: 20.39		ANKH1_HUMAN (922-1013): 2.42e-20: 100: 30.44
+	Hs
		678842 HXA7_HUMAN (17-207): 6.19e-33: 121: 22.40		ANKH1_HUMAN (922-1013): 2.42e-20: 100: 30.44
+	Hs
		839806 LHX2_HUMAN (38-269): 7.77e-34: 128: 14.66		EHMT2_HUMAN (687-995): 4.44e-17: 89.1: 10.35
+	Hs
		678950 HXC8_HUMAN (10-206): 1.06e-30: 116: 22.22		ANKH1_HUMAN (922-1013): 2.42e-20: 100: 30.44
+	Hs
		567802 HXB8_HUMAN (13-224): 1.35e-29: 113: 24.34		ANKH1_HUMAN (922-1013): 2.42e-20: 100: 30.44
+	Hs
		679157 TLX1_HUMAN (79-252): 1.22e-32: 123: 27.32		EHMT2_HUMAN (687-995): 4.44e-17: 89.1: 10.35
+	Hs
		211935 TLX3_HUMAN (42-251): 4.93e-31: 118: 27.11		EHMT2_HUMAN (687-995): 4.44e-17: 89.1: 10.35
+	Hs
		1296426 VSX1_HUMAN (7-231): 4.57e-30: 117: 18.58		EHMT2_HUMAN (687-995): 4.44e-17: 89.1: 10.35
+	Hs
		213370 TLX2_HUMAN (128-211): 1.58e-30: 117: 45.24		EHMT2_HUMAN (687-995): 4.44e-17: 89.1: 10.35
+	Hs
		839785 LHX2_HUMAN (38-269): 7.77e-34: 128: 14.66		KMT2C_HUMAN (222-886): 1.84e-09: 64.7: 11.45
+	Hs
		882142 GSC_HUMAN (3-234): 4.48e-34: 125: 20.34		KMT2C_HUMAN (222-886): 1.84e-09: 64.7: 11.45
+	Hs
		679137 TLX1_HUMAN (79-252): 1.22e-32: 123: 27.32		KMT2C_HUMAN (222-886): 1.84e-09: 64.7: 11.45
+	Hs
		211919 TLX3_HUMAN (42-251): 4.93e-31: 118: 27.11		KMT2C_HUMAN (222-886): 1.84e-09: 64.7: 11.45
+	Hs
		213358 TLX2_HUMAN (128-211): 1.58e-30: 117: 45.24		KMT2C_HUMAN (222-886): 1.84e-09: 64.7: 11.45
+	Hs
		1296405 NKX31_HUMAN (131-226): 1e-11: 65.1: 46.94		EHMT2_HUMAN (687-995): 4.44e-17: 89.1: 10.35