HitPredict

Interactor 1: LSM3 (P62310)
U6 snRNA-associated Sm-like protein LSm3
Gene: LSM3

Interactor 2: LSM10 (Q969L4)
U7 snRNA-associated Sm-like protein LSm10
Gene: LSM10

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.83	1.00	0.912

Property	Details
Experiments	16189514, 15231747, 33961781, 19060904
Identification Methods	two hybrid, affinity chromatography technology, two hybrid array, two hybrid pooling approach, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	LSM~LSM
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 102 Hs			1 123
+	Dm
		1303482 Q8IMX8_DROME (1-102): 1.58e-37: 123: 76.70		Q9VKW8_DROME (18-113): 1.22e-35: 121: 25.77
+	Hs
		974301 LSM3_HUMAN (1-102): 8.92e-41: 131: 100.00		LSM4_HUMAN (18-90): 3.29e-32: 111: 27.03
+	Hs
		974229 LSM3_HUMAN (1-102): 8.92e-41: 131: 100.00		SMD1_HUMAN (17-108): 1.39e-31: 110: 26.09
+	Hs
		974231 LSM3_HUMAN (1-102): 8.92e-41: 131: 100.00		SMD3_HUMAN (18-114): 3.73e-31: 108: 20.62
+	Hs
		974295 LSM3_HUMAN (1-102): 8.92e-41: 131: 100.00		LSM2_HUMAN (19-102): 7.95e-31: 107: 25.58
+	Dm
		1303484 Q8IMX8_DROME (1-102): 1.58e-37: 123: 76.70		Q9VTW6_DROME (19-106): 1.34e-31: 109: 25.56
+	Hs
		973870 LSM3_HUMAN (1-102): 8.92e-41: 131: 100.00		RUXF_HUMAN (20-83): 3.99e-26: 95: 26.56
+	Hs
		974228 LSM3_HUMAN (1-102): 8.92e-41: 131: 100.00		LSM6_HUMAN (6-82): 3.35e-25: 92.3: 27.27
+	Dm
		1477014 SMD2_DROME (13-95): 3.13e-27: 97.8: 30.23		Q9VKW8_DROME (18-113): 1.22e-35: 121: 25.77
+	At
		1425523 Q9FI15_ARATH (23-99): 4.21e-27: 101: 25.00		SMD1B_ARATH (17-110): 7.86e-34: 115: 30.85
+	Hs
		991277 RSMN_HUMAN (23-102): 3.01e-25: 96.2: 23.81		LSM4_HUMAN (18-90): 3.29e-32: 111: 27.03
+	Dm
		1477026 SMD2_DROME (13-95): 3.13e-27: 97.8: 30.23		Q9VTW6_DROME (19-106): 1.34e-31: 109: 25.56
+	Dm
		232183 SMD2_DROME (13-95): 3.13e-27: 97.8: 30.23		SMD3_DROME (18-113): 4.74e-31: 109: 20.83
+	Hs
		974355 RSMN_HUMAN (23-102): 3.01e-25: 96.2: 23.81		SMD1_HUMAN (17-108): 1.39e-31: 110: 26.09
+	Dm
		1477027 SMD2_DROME (13-95): 3.13e-27: 97.8: 30.23		SMD1_DROME (17-108): 4.34e-31: 108: 26.09
+	Hs
		974715 RSMN_HUMAN (23-102): 3.01e-25: 96.2: 23.81		SMD3_HUMAN (18-114): 3.73e-31: 108: 20.62
+	Hs
		991274 RSMN_HUMAN (23-102): 3.01e-25: 96.2: 23.81		LSM2_HUMAN (19-102): 7.95e-31: 107: 25.58
+	Sp
		314072 LSM3_SCHPO (9-98): 2.03e-30: 105: 57.78		LSM2_SCHPO (19-100): 3.06e-25: 93.1: 25.00
+	Hs
		973880 RSMN_HUMAN (23-102): 3.01e-25: 96.2: 23.81		RUXF_HUMAN (20-83): 3.99e-26: 95: 26.56
+	Hs
		974310 RSMN_HUMAN (23-102): 3.01e-25: 96.2: 23.81		LSM6_HUMAN (6-82): 3.35e-25: 92.3: 27.27