HitPredict

Interactor 1: LSM3 (P62310)
U6 snRNA-associated Sm-like protein LSm3
Gene: LSM3

Interactor 2: TFP11 (Q9UBB9)
Tuftelin-interacting protein 11 (Septin and tuftelin-interacting protein 1) (STIP-1)
Gene: TFIP11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.60	0.639

Property	Details
Experiments	27107012, 33961781
Identification Methods	two hybrid, affinity chromatography technology, validated two hybrid, barcode fusion genetics two hybrid, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0005654 - nucleoplasm GO:0071013 - catalytic step 2 spliceosome
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 102 Hs			1 837
+	Hs
		991265 RSMN_HUMAN (23-102): 3.01e-25: 96.2: 23.81		TFP11_HUMAN (1-837): 0: 1109: 100.00
+	Hs
		574498 RSMB_HUMAN (23-102): 1.48e-24: 94.3: 23.81		TFP11_HUMAN (1-837): 0: 1109: 100.00
+	Hs
		974684 SMD2_HUMAN (13-95): 9.28e-26: 94.3: 29.07		TFP11_HUMAN (1-837): 0: 1109: 100.00
+	Sp
		152650 SMD2_SCHPO (4-96): 9.44e-30: 104: 27.37		YKR3_SCHPO (42-835): 0: 697: 23.37
+	Sp
		1082773 RSMB_SCHPO (18-100): 1.17e-22: 87: 22.99		YKR3_SCHPO (42-835): 0: 697: 23.37
+	Hs
		974256 LSM3_HUMAN (1-102): 8.92e-41: 131: 100.00		ZGPAT_HUMAN (41-361): 5.74e-79: 266: 16.19
+	Hs
		574370 RSMB_HUMAN (23-102): 1.48e-24: 94.3: 23.81		ZGPAT_HUMAN (41-361): 5.74e-79: 266: 16.19
+	Hs
		974607 SMD2_HUMAN (13-95): 9.28e-26: 94.3: 29.07		ZGPAT_HUMAN (41-361): 5.74e-79: 266: 16.19
+	Hs
		1327486 LSM5_HUMAN (17-91): 2.31e-25: 92.4: 34.67		ZGPAT_HUMAN (41-361): 5.74e-79: 266: 16.19
+	Hs
		1327477 LSM7_HUMAN (1-97): 3.86e-15: 66.6: 23.71		ZGPAT_HUMAN (41-361): 5.74e-79: 266: 16.19