Interactor 1: PTPS (Q03393)
6-pyruvoyl tetrahydrobiopterin synthase (PTP synthase) (PTPS) (EC 4.2.3.12)
Gene: PTS

Interactor 2: PTPS (Q03393)
6-pyruvoyl tetrahydrobiopterin synthase (PTP synthase) (PTPS) (EC 4.2.3.12)
Gene: PTS

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.982

The method score is based on:

Property Details
Experiments 25416956, 16189514, 21516116, 25910212, 16169070, 32296183, 26264872, 25502805, 24599843, 31515488, unassigned1304
Identification Methods two hybrid, affinity chromatography technology, pull down, two hybrid prey pooling approach, two hybrid array, two hybrid bait and prey pooling approach, validated two hybrid, two hybrid pooling approach
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PTPS~PTPS
Common GO terms GO:0003874 - 6-pyruvoyltetrahydropterin synthase activity
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005829 - cytosol
GO:0006520 - amino acid metabolic process
and 4 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 145
Hs

1 145
+ Mm
+ Dm
+ Ce
+ Ph

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024