Interactor 1: SLD5 (Q03406)
DNA replication complex GINS protein SLD5
Gene: SLD5

Interactor 2: CDC45 (Q08032)
Cell division control protein 45
Gene: CDC45

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.989

The method score is based on:

Property Details
Experiments 17167415, 25342810, 26255844, 25313033, 28373564, 37968396, 21362622, 23499444, 26849847, 16531994, 28355556, 28815832, 31509741, 30104407, 32804080, 32075754, 34700328, 19661920, 19913425, 22325992 and 2 others

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Identification Methods anti tag coimmunoprecipitation, pull down, affinity chromatography technology, biochemical, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains CDC45~Sld5
Common GO terms GO:0000727 - double-strand break repair via break-induced replication
GO:0005634 - nucleus
GO:0006268 - DNA unwinding involved in DNA replication
GO:0031261 - DNA replication preinitiation complex
GO:0031298 - replication fork protection complex
and 2 others

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Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 294
Sc

1 650
+ Hs
+ Mm
+ Dm

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Last updated: 15 Jul 2024