Protein: CROCC
Rootletin (Ciliary rootlet coiled-coil protein)

Gene: CROCC
Organism: Homo sapiens
Interactions: 59
UniProt ID: Q5TZA2

Gene Ontology (top 5):
GO:0001917 - photoreceptor inner segment
GO:0003779 - actin binding
GO:0005198 - structural molecule activity
GO:0005200 - structural constituent of cytoskeleton
GO:0005813 - centrosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

302065

SEGN
Secretagogin

4

2

Small-scale

0.696

High

482912

TPM1
Tropomyosin alpha-1 chain

3

11

High-throughput

0.667

High

1145868

RBP1
RalA-binding protein 1

2

19

High-throughput

0.628

High

324147

CE152
Centrosomal protein of 152 kDa

2

18

Small-scale

0.584

High

396293

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

447778

TPM3
Tropomyosin alpha-3 chain

1

12

High-throughput

0.536

High

1100824

G3BP1
Ras GTPase-activating protein-binding protein 1

1

5

High-throughput

0.536

High

1109802

HDAC1
Histone deacetylase 1

1

20

High-throughput

0.536

High

1216671

UBR1
E3 ubiquitin-protein ligase UBR1

1

1

High-throughput

0.536

High

1216672

UBR2
E3 ubiquitin-protein ligase UBR2

1

1

High-throughput

0.536

High

1216676

KT222
Keratin-like protein KRT222

1

20

High-throughput

0.536

High

1216691

EP15R
Epidermal growth factor receptor substrate 15-like 1

1

14

High-throughput

0.536

High

1216693

SCOC
Short coiled-coil protein

1

1

High-throughput

0.536

High

1216694

GIT1
ARF GTPase-activating protein GIT1

1

7

High-throughput

0.536

High

408919

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

6

High-throughput

0.515

High

1216683

H2B1H
Histone H2B type 1-H

1

20

High-throughput

0.515

High

278872

PEX14
Peroxisomal membrane protein PEX14

1

0

High-throughput

0.513

High

608976

XBP1
X-box-binding protein 1

1

0

High-throughput

0.513

High

777706

VGFR3
Vascular endothelial growth factor receptor 3

1

5

High-throughput

0.500

High

1216679

RN152
E3 ubiquitin-protein ligase RNF152

1

10

High-throughput

0.494

High

1216673

SYCE1
Synaptonemal complex central element protein 1

1

4

High-throughput

0.489

High

1216674

PUSL1
tRNA pseudouridine synthase-like 1

1

1

High-throughput

0.489

High

1216678

SRBD1
S1 RNA-binding domain-containing protein 1

1

4

High-throughput

0.489

High

1216682

TGFA1
Transforming growth factor-beta receptor-associated protein 1

1

18

High-throughput

0.489

High

1216688

HDAC8
Histone deacetylase 8

1

20

High-throughput

0.489

High

1216689

ZY11B
Protein zyg-11 homolog B

1

1

High-throughput

0.489

High

384685

CRYAB
Alpha-crystallin B chain

1

9

High-throughput

0.479

High

468481

HS90B
Heat shock protein HSP 90-beta

1

13

High-throughput

0.479

High

764823

CTNB1
Catenin beta-1

1

14

Small-scale

0.479

High

867195

CAPZB
F-actin-capping protein subunit beta

1

6

High-throughput

0.479

High

876006

TCPE
T-complex protein 1 subunit epsilon

1

10

High-throughput

0.479

High

945013

RAB25
Ras-related protein Rab-25

1

10

High-throughput

0.479

High

1107812

SQSTM
Sequestosome-1

1

11

High-throughput

0.479

High

1216681

SYNE1
Nesprin-1

1

20

Small-scale

0.479

High

1216684

OPTN
Optineurin

1

18

High-throughput

0.479

High

1216687

CP250
Centrosome-associated protein CEP250

1

17

High-throughput

0.479

High

1216690

GAN
Gigaxonin

1

7

High-throughput

0.479

High

1216692

ZRAN1
Ubiquitin thioesterase ZRANB1

1

13

High-throughput

0.479

High

213162

CP110
Centriolar coiled-coil protein of 110 kDa

1

1

High-throughput

0.445

High

765611

BMI1
Polycomb complex protein BMI-1

1

17

High-throughput

0.445

High

1119164

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

10

High-throughput

0.445

High

1216667

A16L1
Autophagy-related protein 16-1

1

20

High-throughput

0.445

High

1216675

CNTRB
Centrobin

1

17

High-throughput

0.445

High

1216680

POC5
Centrosomal protein POC5

1

4

High-throughput

0.445

High

1216685

CEP63
Centrosomal protein of 63 kDa

1

18

High-throughput

0.445

High

1216686

CK5P2
CDK5 regulatory subunit-associated protein 2

1

18

High-throughput

0.445

High

260065

BRD4
Bromodomain-containing protein 4

1

20

High-throughput

0.437

High

588891

RFA2
Replication protein A 32 kDa subunit

1

10

High-throughput

0.437

High

674197

BRD2
Bromodomain-containing protein 2

1

20

High-throughput

0.437

High

695671

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

8

High-throughput

0.437

High

768394

RFA3
Replication protein A 14 kDa subunit

1

8

High-throughput

0.437

High

1201938

BRDT
Bromodomain testis-specific protein

1

20

High-throughput

0.437

High

1216669

DTX2
Probable E3 ubiquitin-protein ligase DTX2

1

10

High-throughput

0.437

High

1216670

MD12L
Mediator of RNA polymerase II transcription subunit 12-like protein

1

14

High-throughput

0.437

High

344217

PTBP3
Polypyrimidine tract-binding protein 3

1

13

High-throughput

0.407

High

372260

MYC
Myc proto-oncogene protein

1

16

High-throughput

0.407

High

1167058

WHAL1
Putative WASP homolog-associated protein with actin, membranes and microtubules-like protein 1

1

4

High-throughput

0.407

High

1216668

CROL1
Putative ciliary rootlet coiled-coil protein-like 1 protein

1

1

High-throughput

0.407

High

1216677

RYBP
RING1 and YY1-binding protein

1

3

High-throughput

0.407

High


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Last updated: 11Aug2025