HitPredict

Interactor 1: TAP1 (Q03518)
Antigen peptide transporter 1 (APT1) (EC 7.4.2.14) (ATP-binding cassette sub-family B member 2) (Peptide supply factor 1) (Peptide transporter PSF1) (PSF-1) (Peptide transporter TAP1) (Peptide transporter involved in antigen processing 1) (Really interesting new gene 4 protein) (RING4)
Gene: TAP1

Interactor 2: TAP2 (Q03519)
Antigen peptide transporter 2 (APT2) (EC 7.4.2.14) (ATP-binding cassette sub-family B member 3) (Peptide supply factor 2) (Peptide transporter PSF2) (PSF-2) (Peptide transporter TAP2) (Peptide transporter involved in antigen processing 2) (Really interesting new gene 11 protein) (RING11)
Gene: TAP2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.978

The method score is based on:

Property Details
Experiments 28514442, 33961781, 35961308, 30833792, 11381133, 17055437, 19297616, 26789246, 18802093, 12213826, 19201886, 16828748
Identification Methods affinity chromatography technology, pull down, cross-linking study, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains ABC_membrane~ABC_membrane, ABC_membrane~ABC_tran, ABC_tran~ABC_tran
Common GO terms GO:0005524 - ATP binding
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane
GO:0015031 - protein transport
GO:0015433 - ABC-type peptide antigen transporter activity
and 13 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 748
Hs

1 686
+ Hs
+ Rn
+ Rn
+ Hs
+ Rn
+ Hs
+ Mm
+ Hs
+ Mm
+ Ce
+ Sc
+ Vc
+ Ec
+ At
+ Hs

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Last updated: 15 Jul 2024