HitPredict

Interactor 1: PO3F4 (P62516)
POU domain, class 3, transcription factor 4 (Brain-specific homeobox/POU domain protein 4) (Brain-4) (Brn-4) (Octamer-binding protein 9) (Oct-9) (Octamer-binding transcription factor 9) (OTF-9) (RHS2 class III POU protein)
Gene: Pou3f4

Interactor 2: PO3F4 (P62516)
POU domain, class 3, transcription factor 4 (Brain-specific homeobox/POU domain protein 4) (Brain-4) (Brn-4) (Octamer-binding protein 9) (Oct-9) (Octamer-binding transcription factor 9) (OTF-9) (RHS2 class III POU protein)
Gene: Pou3f4

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.46 1.00 0.680

The method score is based on:

Property Details
Experiments 9105675
Identification Methods far western blotting, two hybrid
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Homeodomain~Homeodomain, Homeodomain~Pou, Pou~Pou
Common GO terms GO:0000977 - RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003680 - minor groove of adenine-thymine-rich DNA binding
GO:0003690 - double-stranded DNA binding
and 11 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 361
Rn

1 361
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Mm
+ Hs
+ Mm
+ Dm
+ Dm
+ Dm
+ Hs
+ Mm
+ Mm
+ Mm
+ Hs

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Last updated: 11Aug2025