Protein: PIT1
Pituitary-specific positive transcription factor 1 (PIT-1) (Growth hormone factor 1) (GHF-1)

Gene: PIT1, POU1F1
Organism: Homo sapiens
Interactions: 31
UniProt ID: P28069

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 - DNA-binding transcription activator activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

700815

MSX2
Homeobox protein MSX-2

2

20

High-throughput

0.783

High

700832

LHX4
LIM/homeobox protein Lhx4

2

20

High-throughput

0.783

High

700820

PITX1
Pituitary homeobox 1

1

19

Small-scale

0.680

High

662375

GATA2
Endothelial transcription factor GATA-2

2

11

Small-scale

0.646

High

278245

NCOR1
Nuclear receptor corepressor 1

2

18

Small-scale

0.624

High

700821

PO5F1
POU domain, class 5, transcription factor 1

1

15

High-throughput

0.618

High

700818

KR108
Keratin-associated protein 10-8

2

20

High-throughput

0.606

High

700822

ARI5A
AT-rich interactive domain-containing protein 5A

2

17

High-throughput

0.606

High

700827

KRA61
Keratin-associated protein 6-1

2

1

High-throughput

0.606

High

700828

KR151
Keratin-associated protein 15-1

2

2

High-throughput

0.606

High

700835

ARIP4
Helicase ARIP4

2

20

High-throughput

0.606

High

700826

MED1
Mediator of RNA polymerase II transcription subunit 1

1

11

Small-scale

0.561

High

700831

CBP
CREB-binding protein

1

20

Small-scale

0.561

High

700824

LASP1
LIM and SH3 domain protein 1

2

3

High-throughput

0.553

High

700814

KINH
Kinesin-1 heavy chain

1

3

High-throughput

0.536

High

700829

MRCKG
Serine/threonine-protein kinase MRCK gamma

1

4

High-throughput

0.536

High

282923

NR1I2
Nuclear receptor subfamily 1 group I member 2

1

20

Small-scale

0.501

High

403842

GCR
Glucocorticoid receptor

1

20

Small-scale

0.501

High

429351

JUN
Transcription factor Jun

1

10

Small-scale

0.501

High

543463

VDR
Vitamin D3 receptor

1

20

Small-scale

0.501

High

577408

ETS1
Protein C-ets-1

1

12

Small-scale

0.501

High

700816

PPARG
Peroxisome proliferator-activated receptor gamma

1

20

Small-scale

0.501

High

700823

PPARA
Peroxisome proliferator-activated receptor alpha

1

20

Small-scale

0.501

High

700825

NR1I3
Nuclear receptor subfamily 1 group I member 3

1

20

Small-scale

0.501

High

245424

OPA1
Dynamin-like GTPase OPA1, mitochondrial

1

0

High-throughput

0.493

High

700834

ERP44
Endoplasmic reticulum resident protein 44

1

3

High-throughput

0.489

High

700819

UBC9
SUMO-conjugating enzyme UBC9

1

4

High-throughput

0.481

High

700817

CEBPD
CCAAT/enhancer-binding protein delta

1

12

Small-scale

0.479

High

700830

Q7KZS0
SUMO-conjugating enzyme UBC9

1

4

High-throughput

0.470

High

582309

ARSA
Arylsulfatase A

2

0

High-throughput

0.316

High

700833

DDT4L
DNA damage-inducible transcript 4-like protein

1

0

High-throughput

0.268

Low


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Last updated: 11Aug2025